全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:John Coote , Emily Allen ...
来源:[J].International Journal of Cardiology(IF 5.509), 2018, Vol.264, pp.70-78Elsevier
摘要:Abstract(#br)Background(#br)Studies have shown regional and functional selectivity of cardiac postganglionic neurones indicating there might exist a similar heterogeneity in spinal segmental preganglionic neurones, which requires further investigation.(#br)Methods(#br)Right ...
作者:John Coote , Emily Allen ...
来源:[J].International Journal of Cardiology(IF 5.509), 2018, Vol.264, pp.70-78Elsevier
摘要:Abstract(#br)Background(#br)Studies have shown regional and functional selectivity of cardiac postganglionic neurones indicating there might exist a similar heterogeneity in spinal segmental preganglionic neurones, which requires further investigation.(#br)Methods(#br)Right ...
作者:... John N Townend , John Coote , Robert S Bonser
来源:[J].Journal of the American College of Cardiology(IF 14.086), 2002, Vol.39 (1), pp.102-108Elsevier
摘要:Abstract(#br)Objectives(#br)We investigated the interaction of heart rate (HR), temperature and contractility using a validated load independent method.(#br)Background(#br)Temperature manipulation is an integral part of cardiac surgery, and postoperative hypothermia is extre...
作者:... Barry Moore , Roger Parton , John Coote
来源:[J].Vaccine(IF 3.492), 2014, Vol.32 (33), pp.4234-4242Elsevier
摘要:Abstract(#br)Protein-coated microcrystals (PCMCs) were investigated as potential vaccine formulations for a range of model antigens. Presentation of antigens as PCMCs increased the antigen-specific IgG responses for all antigens tested, compared to soluble antigens. When compared...
作者:Sarah Othman , Roger Parton , John Coote
来源:[J].Microbial Pathogenesis(IF 1.974), 2012, Vol.52 (6), pp.353-358Elsevier
摘要:Abstract(#br)A Pasteurella multocida B:2 strain from a case of bovine haemorrhagic septicaemia (HS) and a derivative, JRMT12, that was attenuated by a deletion in the aroA gene, were shown to adhere to, invade and survive within cultured embryonic bovine lung (EBL) cells. By comp...
作者:... Susan Baillie , Roger Parton , John Coote
来源:[J].Vaccine(IF 3.492), 2006, Vol.25 (1), pp.64-71Elsevier
摘要:Abstract(#br)This study examined the ability of the adenylate cyclase toxin (CyaA) of Bordetella pertussis to act as a mucosal adjuvant for other antigens when co-administered by the intranasal route in mice. Two forms of CyaA were used: the cell-invasive, enzymically active form...
作者:Kalantar Hormozi , Roger Parton , John Coote
来源:[J].FEMS Immunology and Medical Microbiology(IF 2.684), 1999, Vol.23 (4), pp.273-282Elsevier
摘要:Abstract(#br)Bordetella pertussis produces a cell-invasive adenylate cyclase toxin which is synthesised from the cyaA gene as an inactive protoxin that is post-translationally activated by the product of the cyaC gene. Purified active and inactive CyaA proteins were prepared from...
作者:Kalantar Hormozi , Roger Parton , John Coote
来源:[J].FEMS Microbiology Letters(IF 2.049), 1998, Vol.169 (1), pp.139-145Elsevier
摘要:Abstract(#br)The leukotoxin (LktA) of Pasteurella haemolytica is active only against cells of ruminant origin. It is synthesised as an inactive protoxin encoded by the lktA gene and post-translationally modified to the active toxin by the product of the lktC gene. The LktA and Lk...
作者:... Susan Baillie , Roger Parton , John Coote
来源:[J].Vaccine(IF 3.492), 2004, Vol.22 (31), pp.4270-4281Elsevier
摘要:Abstract(#br)The cell-invasive adenylate cyclase toxin (CyaA) of Bordetella pertussis was shown to be highly antigenic in mice, stimulating serum anti-CyaA IgG antibody responses which were able to neutralise the cytotoxic effect of CyaA on J774.2 macrophage-like cells. The ...

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