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作者:... Nicola Avery , Johanna Kela , Claes Wahlestedt
来源:[J].European Journal of Pharmacology(IF 2.592), 2000, Vol.388 (1), pp.R1-R2
摘要:Abstract(#br)The injection of a dopamine D 2 receptor hammerhead ribozyme (20 μg) once daily for 5 days into the nucleus accumbens of rats resulted in an inhibition of stereotyped sniffing and locomotor activation produced by the selective dopamine D 2 receptor agonist, quin...
作者:Johanna Kela , Ulf Arvidsson
来源:[J].European Journal of Pharmacology(IF 2.592), 2003, Vol.458 (1), pp.101-106
摘要:Abstract(#br)The selective δ-opioid receptor agonist deltorphin II (25.0–100.0 μg, i.c.v.) produced biphasic effects on core temperature in rats, in which hypothermia was followed by hyperthermia. Pretreatment with the selective δ-opioid receptor antagonist, naltrindole...
作者:Johanna Kela , Peter Salmi ...
来源:[J].Regulatory Peptides(IF 2.056), 2003, Vol.114 (2), pp.109-114
摘要:Abstract(#br)Melanin-concentrating hormone (MCH) is a cyclic neuropeptide, predominantly expressed in hypothalamus, and recognized as a key regulator in feeding behaviour and energy balance. In this study, we examined the behavioural effects of intracerebroventricularly admi...
作者:Johanna Kela , Françoise Lallemand ...
来源:[J].Mammalian Genome(IF 2.419), 1999, Vol.10 (1), pp.30-34
摘要:Abstract.(#br) The rat Chromosome (Chr) 2 harbors several genes controlling tumor growth or development, blood pressure, and non-insulin-dependent diabetes mellitus. We report that the region (2q1) containing the mammary susceptibility cancer gene Mcs1 also harbors the genes enco...
作者:Johanna Kela , Thomas Johnsson ...
来源:[J].Proceedings of the National Academy of Sciences of the United States of America(IF 9.737), 2000, Vol.97 (10), pp.5633-5638
摘要:Insufficient efficacy and/or specificity of antisense oligonucleotides limit their in vivo usefulness. We demonstrate here that a high-affinity DNA analog, locked nucleic acid (LNA), confers several desired properties to antisense agents. Unlike DNA, LNA/DNA copolymers were not d...
作者:Johanna Kela , Francoise Lallemand ...
来源:[J].Journal of Experimental Animal Science, 2000, Vol.41 (1), pp.38-39
摘要:Summary(#br)The rat map was improved by determining the regional chromosome localization of 82 genes, thereby orienting each linkage group. New anonymous markers were also generated on rat chromosome 2.

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