全部文献期刊会议图书|学者科研项目
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作者:... Jun-Mo Yang , Jinhyuk Lee , Yong-Doo Park
来源:[J].International Journal of Biological Macromolecules(IF 2.596), 2018, Vol.113, pp.212-218
摘要:Abstract(#br)Inhibition of α-glucosidase is directly associated with treatment of type 2 diabetes. In this regard, we conducted enzyme kinetics integrated with computational docking simulation to assess the inhibitory effect of raspberry ketone (RK) on α-glucosidase. RK boun...
作者:Jinhyuk Lee , Li-Mei Yue ...
来源:[J].International Journal of Biological Macromolecules(IF 2.596), 2018, Vol.112, pp.686-693
摘要:Abstract(#br)In this study we conducted serial kinetic studies integrated with computational simulations to judge the inhibitory effect of pyrogallol on α-glucosidase, due to the association between this enzyme and the treatment of type 2 diabetes. As a result, we found that...
作者:Jinhyuk Lee , GyuTae Lim ...
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2018
摘要:Abstract(#br)Mitochondrial dysfunction and subsequent enhanced oxidative stress is implicated in the pathogenesis of autism spectrum disorder (ASD). Mitochondrial transcription factor B2 (TFB2M) is an essential protein in mitochondrial gene expression. No reports have described T...
作者:Jinhyuk Lee , Myung-hee Lee ...
来源:[J].Journal of Functional Foods(IF 2.632), 2019, Vol.52, pp.442-449
摘要:Abstract(#br)This study suggests sulfuretin as an ant-skin aging agent. Sulfuretin significantly reduces solar UV (sUV)-increased matrix metalloproteinase-1 (MMP-1) expression and c-Jun phosphorylation in human dermal fibroblasts as well as skin tissue. An examination of the...
作者:... Hao Hao , Jinhyuk Lee , Yong-Doo Park
来源:[J].International Journal of Biological Macromolecules(IF 2.596), 2017, Vol.101, pp.32-39
摘要:Abstract(#br)The α-glucosidase inhibitor is of interest to researchers due to its association with type-2 diabetes treatment. Hesperetin is a flavonoid with natural antioxidant properties. This paper presents an evaluation on the effects of hesperetin on α-glucosidase via in...
作者:Jinhyuk Lee , Hao Hao ...
来源:[J].International Journal of Biological Macromolecules(IF 2.596), 2017, Vol.105
摘要:Abstract(#br)Creatine kinase (EC 2.7.3.2, CK) plays an important role in cellular energy metabolism and homeostasis by catalyzing the transfer of phosphate between ATP and creatine phosphate. In this study, we investigated the effects of H 2 O 2 on PSCKM (muscle type creatine kin...
作者:Jinhyuk Lee , Xiao-Bao Sun ...
来源:[J].International Journal of Biological Macromolecules(IF 2.596), 2018
摘要:Abstract(#br)Regulation of α-glucosidase (EC 3.2.1.20) and its inhibitors is of great interest to researchers due to its clinical relevance as a target enzyme for the treatment of α-glucosidase-mediated diseases, such as type 2 diabetes mellitus and Pompe disease. In this st...
作者:Jinhyuk Lee , Li Zheng ...
来源:[J].International Journal of Biological Macromolecules(IF 2.596), 2017, Vol.103, pp.829-838
摘要:Abstract(#br)Due to the finding that inhibition of α-glucosidase is directly associated with treatment of several diseases, the development of a selective inhibitor for targeting α-glucosidase is important. Gallotannin (GT) is a natural ingredient that has been used as a foo...
作者:Jinhyuk Lee , Raehyun Kim ...
来源:[J].Information Sciences(IF 3.643), 2018, Vol.457-458, pp.1-11
摘要:Abstract(#br)Anomaly detection in an industrial process is crucial for preventing unexpected economic loss. Among various signals, multivariate time series signals are one of the most difficult signals to analyze for detecting anomalies. Moreover, labels for anomalous signals are...
作者:Jinhyuk Lee , Yue-Xiu Si ...
来源:[J].International Journal of Biological Macromolecules(IF 2.596), 2018
摘要:Abstract(#br)Pyrogallol is naturally found in aquatic plant and has been proposed as a substrate of tyrosinase. In this study, we evaluated the dual effect of pyrogallol on tyrosinase as an inhibitor in the presence of L‑DOPA simultaneously via integrating methods of enzyme ...

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