全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Jiejie Liu , Yijun Li ...
来源:[J].Diabetology & Metabolic Syndrome(IF 1.924), 2017, Vol.9 (1)Springer
摘要:Type 2 diabetes mellitus (T2DM), which is characterized by the combination of relative insulin deficiency and insulin resistance, cannot be reversed with existing therapeutic strategies. Transplantation of insulin-producing cells (IPCs) was once thought to be the most promising s...
作者:Jiejie Liu , Liang Dong ...
来源:[J].Stem Cell Research & Therapy(IF 3.652), 2017, Vol.8 (1)Springer
摘要:Insulin resistance is one of the most common and important pathological features of type 2 diabetes (T2D). Recently, insulin resistance is increasingly considered to be associated with systemic chronic inflammation. Elevated levels of tumor necrosis factor (TNF)-α and interl...
作者:Jiejie Liu , Dongdong Ti ...
来源:[J].PLoS ONE(IF 3.73), 2018, Vol.8 (3)DOAJ
摘要:Mesenchymal stem cells (MSCs) hold great therapeutic potential. However, MSCs undergo replication senescence during the in vitro expansion process. Wharton's jelly from the human umbilical cord harbors a large number of MSCs. In this study, we hypothesized that Wharton's jel...
作者:Jiejie Liu , Liang Dong ...
来源:[J].Journal of Translational Medicine(IF 3.459), 2015, Vol.13 (1)Springer
摘要:Abstract(#br) Background(#br)Within the last few years, it has become evident that LPS-preconditioned mesenchymal stromal cells (LPS pre-MSCs) show enhanced paracrine effects, including increased trophic support and improved regenerative and repair properties. MSCs may relea...
作者:... Chunsun Li , Jiejie Liu , Liangan Chen
来源:[J].Cellular Physiology and Biochemistry(IF 3.415), 2015, Vol.37 (5), pp.1830-1846DOAJ
摘要:Background/Aims: Mesenchymal stem cell (MSC) based therapies may be useful for treating acute respiratory distress syndrome (ARDS), but the underlying mechanisms are incompletely understood. We investigated the impact of human umbilical cord Wharton's jelly-derived MSC (hUC-MSC) ...
作者:Jiejie Liu , Jieqing Gao ...
来源:[J].Cell Death and Disease(IF 6.044), 2018, Vol.9 (7), pp.1-18DOAJ
摘要:Abstract Progressive pancreatic β-cell dysfunction is recognized as a fundamental pathology of type 2 diabetes (T2D). Recently, mesenchymal stem cells (MSCs) have been identified in protection of islets function in T2D individuals. However, the underlying mechanisms remain e...
作者:Jiejie Liu , Liang Dong ...
来源:[J].Stem Cell Research & Therapy(IF 3.652), 2017, Vol.8 (1), pp.1-14DOAJ
摘要:Abstract Background Insulin resistance is one of the most common and important pathological features of type 2 diabetes (T2D). Recently, insulin resistance is increasingly considered to be associated with systemic chronic inflammation. Elevated levels of tumor necrosis facto...
作者:Jiejie Liu , Zongyan Xie ...
来源:[J].International Immunopharmacology(IF 2.417), 2018, Vol.60, pp.235-245Elsevier
摘要:Abstract(#br)Umbilical cord-derived mesenchymal stem cells (UC-MSCs), with both immunomodulatory and pro-regenerative properties, are promising for the treatment of type 2 diabetes mellitus (T2DM). As efficient cell therapy largely relies on appropriate homing to target tissues, ...

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