全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Jiamin Xiao , Xiaojing Tang ...
来源:[J].BMC Bioinformatics(IF 3.024), 2011, Vol.12 (1)Springer
摘要:Abstract(#br) Background(#br)MicroRNAs (miRNAs) play a key role in regulating various biological processes such as participating in the post-transcriptional pathway and affecting the stability and/or the translation of mRNA. Current methods have extracted feature information at d...
作者:Jiamin Xiao , Hui Yin ...
来源:[J].BMC Bioinformatics(IF 3.024), 2011, Vol.12 (1)Springer
摘要:Abstract(#br) Background(#br)The rapid accumulation of data on non-synonymous single nucleotide polymorphisms (nsSNPs, also called SAPs) should allow us to further our understanding of the underlying disease-associated mechanisms. Here, we use complex networks to study the role o...
作者:... Mei Hu , Jiamin Xiao , Menglong Li
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.6 (3)DOAJ
摘要:Owing to their potential for systematic analysis, complex networks have been widely used in proteomics. Representing a protein structure as a topology network provides novel insight into understanding protein folding mechanisms, stability and function. Here, we develop a new feat...
作者:Jiamin Xiao , Yizhou Li ...
来源:[J].Chemometrics and Intelligent Laboratory Systems(IF 2.291), 2012, Vol.118, pp.317-323Elsevier
摘要:Abstract(#br)The improvement of computational methods greatly benefits the investigation of miRNAs. Our study validates the features in miRNA identification with an independent dataset, and provides researchers with common practices of the development of predictive models. A tota...
作者:Jiamin Xiao , Yizhou Li ...
来源:[J].Computational Biology and Chemistry(IF 1.793), 2011, Vol.35 (3), pp.131-136Elsevier
摘要:Abstract(#br)MicroRNA (miRNA) is the negative regulator of gene expression, also known as guide strand of transient miRNA:miRNA* duplex. It is critical in maintaining the normal physiological processes such as development, differentiation, and apoptosis in many organisms. Wi...
作者:Jiamin Xiao , Xia Wang ...
来源:[J].Journal of Theoretical Biology(IF 2.351), 2010, Vol.267 (3), pp.312-318Elsevier
摘要:Abstract(#br)A three-stage support vector machine (SVM) was constructed to predict the state of cysteines by fusing sequence information, evolution information and annotation information of protein sequences. The first and second stages were for predicting whether the protein seq...
作者:Jiamin Xiao , Fuyuan Tan
来源:[J].Amino Acids(IF 3.914), 2010, Vol.38 (5), pp.1497-1503Springer
摘要:Abstract(#br)Membrane transporters are critical in living cells. Therefore, the discrimination of the types of membrane proteins based on their functions is of great importance both for helping genome annotation and providing a supplementary role to experimental researchers ...
作者:... Yaping Fang , Jiamin Xiao , Menglong Li
来源:[J].Amino Acids(IF 3.914), 2011, Vol.40 (1), pp.239-248Springer
摘要:Abstract(#br)RNA–protein interactions play a pivotal role in various biological processes, such as mRNA processing, protein synthesis, assembly, and function of ribosome. In this work, we have introduced a computational method for predicting RNA-binding sites in proteins bas...

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