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作者:Jia-Yang Hong , Thomas Walz ...
来源:[J].Cellular and Molecular Life Sciences(IF 5.615), 2012, Vol.69 (4), pp.641-650Springer
摘要:Abstract(#br)In the cell, many small endogenous metabolic molecules are involved in distinct cellular functions such as modulation of chromatin structure and regulation of gene expression. O -acetyl-ADP-ribose (AAR) is a small metabolic molecule that is generated during NAD-depen...
作者:Jia-Yang Hong , Kuan-Chung Su
来源:[C].Abstracts of BIT's 4th Annual World Congress of Molecular & Cell Biology-20142014CNKI
摘要:A lot of endogenous cellular small molecules are involved in many biological functions such as regulation of gene expression and modulation of chromatin structure.O-acetyl-ADP-ribose(AAR) is an epigenetic related small molecule that is generated during NAD-dependent deacetylation...
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作者:Sue-Hong Wang , Sue-Ping Lee ...
来源:[J].Genes, 2019, Vol.10 (8)MDPI
摘要:O-acetyl-ADP-ribose (AAR) is a metabolic small molecule relevant in epigenetics that is generated by NAD-dependent histone deacetylases, such as Sir2. The formation of silent heterochromatin in yeast requires histone deacetylation by Sir2, structural rearrangement of SIR complexe...

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