全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Nicholas T. Funderburg , Timothy A. Haystead , Jesse J. Kwiek
来源:[J].Retrovirology(IF 5.657), 2017, Vol.14 (1)Springer
摘要:Like all viruses, HIV-1 relies on host systems to replicate. The human purinome consists of approximately two thousand proteins that bind and use purines such as ATP, NADH, and NADPH. By virtue of their purine binding pockets, purinome proteins are highly druggable, and many exis...
作者:Jesse J. Kwiek , Robert A. Baiocchi
来源:[J].Viruses(IF 2.509), 2015, Vol.8 (1)DOAJ
摘要:Human T-cell leukemia virus type-1 (HTLV-1) is a tumorigenic retrovirus responsible for development of adult T-cell leukemia/lymphoma (ATLL). This disease manifests after a long clinical latency period of up to 2–3 decades. Two viral gene products, Tax and HBZ, have transfor...
作者:Jesse J. Kwiek , Susan A. Fiscus ...
来源:[J].Diagnostic Microbiology & Infectious Disease(IF 2.26), 2009, Vol.66 (4), pp.356-360Elsevier
摘要:Abstract(#br)There are limited data on acute HIV infection (AHI) prevalence during pregnancy. Malawian pregnant women admitted in the third trimester and meeting eligibility criteria underwent dual HIV rapid antibody testing. AHI prevalence was retrospectively detected throu...
作者:Jesse J. Kwiek , Wolfgang Sadee ...
来源:[J].Computers in Biology and Medicine(IF 1.162), 2015, Vol.58, pp.1-13Elsevier
摘要:Abstract(#br)Background(#br)Associations between genotype and phenotype provide insight into the evolution of pathogenesis, drug resistance, and the spread of pathogens between hosts. However, common ancestry can lead to apparent associations between biologically unrelated featur...
作者:... Courtney Maierhofer , Jan Clark , Jesse J. Kwiek
来源:[J].JAIDS Journal of Acquired Immune Deficiency Syndromes(IF 4.653), 2018, Vol.79 (1), pp.1-9Wolters Kluwer
摘要:BACKGROUND:: Worldwide, nearly 18 million women of reproductive age are living with HIV-1. Although increased access to antiretroviral therapy (ART) during pregnancy has significantly reduced HIV-1 mother-to-child transmission (MTCT), a similarly robust reduction in preterm ...
作者:Jesse J. Kwiek , Tomoko Ishikawa ...
来源:[J].Histochemistry and Cell Biology(IF 2.613), 2013, Vol.139 (3), pp.487-500Springer
摘要:Abstract(#br)A proteomics survey of human placental syncytiotrophoblast (ST) apical plasma membranes revealed peptides corresponding to flotillin-1 (FLOT1) and flotillin-2 (FLOT2). The flotillins belong to a class of lipid microdomain-associated integral membrane proteins that ha...
作者:... James A. Matous , Jesse J. Kwiek , Don M. Coltart
来源:[J].Bioorganic & Medicinal Chemistry Letters(IF 2.338), 2011, Vol.21 (8), pp.2406-2409Elsevier
摘要:Abstract(#br)The total asymmetric synthesis of (+)- and (−)-clusianone and (+)- and (−)-clusianone methyl enol ether is reported. Asymmetric induction is achieved through the use of ACC alkylation, providing the key intermediates with an er of 99:1. The four synthetic compou...

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