全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Josh L. Morgan , Jeff W. Lichtman
来源:[J].BMC Biology(IF 6.531), 2017, Vol.15 (1)Springer
摘要:Imaging as a means of scientific data storage has evolved rapidly over the past century from hand drawings, to photography, to digital images. Only recently can sufficiently large datasets be acquired, stored, and processed such that tissue digitization can actually reveal more t...
作者:... Miranda A. Chacon , Adriaan O. Grobbelaar , Jeff W. Lichtman
来源:[J].Journal of Surgical Research(IF 2.018), 2019, Vol.242, pp.207-213Elsevier
摘要:Abstract(#br)Background(#br)Peripheral nerve assessment has traditionally been studied through histological and immunological staining techniques in a limited cross-sectional modality, making detailed analysis difficult. A new application of serial section electron microscop...
作者:... Richard Schalek , Jeff W. Lichtman , Ronald L. Walsworth
来源:[J].Small(IF 7.823), 2017, Vol.13 (22), pp.n/a-n/aWiley
摘要:Correlated electron microscopy and cathodoluminescence (CL) imaging using functionalized nanoparticles is a promising nanoscale probe of biological structure and function. Nanodiamonds (NDs) that contain CL‐emitting color centers are particularly well suited for such applica...
作者:Douglas S. Richardson , Jeff W. Lichtman
来源:[J].Cell(IF 31.957), 2015, Vol.162 (2), pp.246-257Elsevier
摘要:Biological specimens are intrinsically three dimensional; however, because of the obscuring effects of light scatter, imaging deep into a tissue volume is problematic. Although efforts to eliminate the scatter by “clearing” the tissue have been ongoing for over a century, th...
作者:Jeff W. Lichtman , Tom A. Rapoport
来源:[J].Cell(IF 31.957), 2013, Vol.154 (2), pp.285-296Elsevier
摘要:Summary(#br)The endoplasmic reticulum (ER) often forms stacked membrane sheets, an arrangement that is likely required to accommodate a maximum of membrane-bound polysomes for secretory protein synthesis. How sheets are stacked is unknown. Here, we used improved staining and auto...
作者:... Cristina Guatimosim , H. Sebastian Seung , Jeff W. Lichtman
来源:[J].Neuron(IF 15.766), 2012, Vol.74 (5), pp.816-829Elsevier
摘要:Summary(#br)Using light and serial electron microscopy, we show profound refinements in motor axonal branching and synaptic connectivity before and after birth. Embryonic axons become maximally connected just before birth when they innervate ∼10-fold more muscle fibers than ...
作者:Jeff W. Lichtman , Jean Livet ...
来源:[J].Current Biology(IF 9.494), 2013, Vol.23 (1), pp.21-31Elsevier
摘要:Summary(#br)Background(#br)The cleavage-stage mouse embryo is composed of superficially equivalent blastomeres that will generate both the embryonic inner cell mass (ICM) and the supportive trophectoderm (TE). However, it remains unsettled whether the contribution of each blastom...

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