全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
中外文文献  中文文献  外文文献
作者:Jeanne Kowalski , C Conover Talbot ...
来源:[J].BMC Genomics(IF 4.397), 2011, Vol.12 (1)Springer
摘要:Abstract(#br) Background(#br)Although the high mobility group A1 ( HMGA1 ) gene is widely overexpressed in diverse cancers and portends a poor prognosis in some tumors, the molecular mechanisms that mediate its role in transformation have remained elusive. HMGA1 functions as a po...
作者:... Michael Kutner , Fadlo R. Khuri , Jeanne Kowalski
来源:[J].Contemporary Clinical Trials(IF 1.597), 2014, Vol.37 (2), pp.322-332Elsevier
摘要:Abstract(#br)The primary purposes of Phase I cancer clinical trials are to determine the maximum tolerated dose (MTD) and the treatment schedule of a new drug. Phase I trials usually involve a small number of patients so that fully utilizing all toxicity information including tim...
作者:Jeanne Kowalski , Deborah W. Bruner
来源:[J].Brain Behavior and Immunity(IF 5.612), 2016, Vol.52, pp.145-152Elsevier
摘要:Abstract(#br)Patients with head and neck cancer (HNC) receiving intensity-modulated radiation therapy (IMRT) have particularly high rates of fatigue, and pre- and post-radiotherapy fatigue are prognostic factors for pathologic tumor responses and poor survival. Although inflammat...
作者:... Walter J. Curran , Fadlo Khuri , Jeanne Kowalski
来源:[J].Contemporary Clinical Trials(IF 1.597), 2015, Vol.43, pp.133-141Elsevier
摘要:Abstract(#br)To save valuable time and resources in new drug development, Phase I/II clinical trials with toxicity control and drug efficacy as dual primary endpoints have become increasingly popular. Escalation with over-dose control (the EWOC) is a Bayesian adaptive Phase I cli...
作者:Jeanne Kowalski , Adam J. Perricone ...
来源:[J].Biology of Blood and Marrow Transplantation(IF 3.94), 2019, Vol.25 (6), pp.1075-1084Elsevier
摘要:ABSTRACT(#br)A higher number of donor plasmacytoid dendritic cells (pDCs) is associated with increased survival and reduced graft-versus-host disease (GVHD) in human recipients of unrelated donor bone marrow (BM) grafts, but not granulocyte colony-stimulating factor (G-CSF)-...
作者:Zhengjia Chen , Mourad Tighiouart , Jeanne Kowalski
来源:[J].Contemporary Clinical Trials(IF 1.597), 2012, Vol.33 (5), pp.949-958Elsevier
摘要:Abstract(#br)Escalation with overdose control (EWOC) is a Bayesian adaptive design for selecting dose levels in cancer Phase I clinical trials while controlling the posterior probability of exceeding the maximum tolerated dose (MTD). EWOC has been used by clinicians to desig...
作者:Jeanne Kowalski , Jeffrey J. Olson ...
来源:[J].Journal of Neuro-Oncology(IF 3.115), 2019, Vol.143 (3), pp.381-392Springer
摘要:Abstract(#br) Purpose(#br)Gliosarcoma is a histologic variant of glioblastoma (GBM), and like GBM carries a poor prognosis. Median survival is less than one (1) year with less than 5% of patients alive after 5 years. Although there is no cure, standard treatment includes sur...
作者:... Alexis B Carter , Jeanne Kowalski , Tobey J MacDonald
来源:[J].Translational Oncology(IF 3.393), 2019, Vol.12 (7), pp.908-916DOAJ
摘要:Host genome analysis is a promising source of predictive information for long-term morbidity in cancer survivors. However, studies on genetic predictors of long-term outcome, particularly neurocognitive function following chemoradiation in pediatric oncology, are limited. Here, w...

我们正在为您处理中,这可能需要一些时间,请稍等。

资源合作:cnki.scholar@cnki.net, +86-10-82896619   意见反馈:scholar@cnki.net

×