全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Jean-Laurent Thibaud , Thomas Voit ...
来源:[J].BMC Musculoskeletal Disorders(IF 1.875), 2011, Vol.12 (1)Springer
摘要:Abstract(#br) Background(#br)This study aimed to measure the gait abnormalities in GRMD (Golden retriever muscular dystrophy) dogs during growth and disease progression using an ambulatory gait analyzer (3D-accelerometers) as a possible tool to assess the effects of a therapeutic...
作者:Jean-Laurent Thibaud , Inès Barthélémy ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.7 (10)DOAJ
摘要:Centronuclear myopathies (CNM) are inherited congenital disorders characterized by an excessive number of internalized nuclei. In humans, CNM results from ~70 mutations in three major genes from the myotubularin, dynamin and amphiphysin families. Analysis of animal models with al...
作者:... Yves Unterfinger , Jean-Laurent Thibaud , Stéphane Blot
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.7 (11)DOAJ
摘要:The GRMD (Golden retriever muscular dystrophy) dog has been widely used in pre-clinical trials targeting DMD (Duchenne muscular dystrophy), using in many cases a concurrent immune-suppressive treatment. The aim of this study is to assess if such a treatment could have an effect o...
作者:Jean-Laurent Thibaud , Dennilyn L. Parker
来源:[J].Journal of Exotic Pet Medicine(IF 0.4), 2019, Vol.31, pp.104-107Elsevier
摘要:Abstract(#br)Vestibular signs are rarely reported in ferrets. This report documents the successful diagnosis and management of an otitis interna without otitis media in a ferret. A 4-year-old deslorelin-implanted female ferret presented with an acute-onset, 2-day history of circl...
作者:Jean-Laurent Thibaud , Benoît Hédan ...
来源:[J].Human Genetics(IF 4.633), 2019, Vol.138 (5), pp.455-466Springer
摘要:Abstract(#br)In humans, hereditary sensory neuropathies (HSN), also known as hereditary sensory and autonomic neuropathies (HSAN), constitute a clinically and genetically heterogeneous group of disorders characterized by progressive sensory loss, often accompanied by chronic skin...
作者:Jean-Laurent Thibaud , Bijan Ghaleh ...
来源:[J].Basic Research in Cardiology(IF 5.904), 2012, Vol.107 (1), pp.1-9Springer
摘要:Abstract(#br)Little is known about the vascular function and expression of endothelial and neuronal nitric oxide synthases (eNOS and nNOS) in Duchenne muscular dystrophy (DMD). Bradykinin is involved in the regulation of eNOS expression induced by angiotensin-converting enzy...
作者:Jean-Laurent Thibaud , Françoise Delisle
来源:[J].Journal of Feline Medicine and Surgery(IF 1.08), 2007, Vol.9 (4), pp.340-345Elsevier
摘要:Spinal epidural empyema (SEE) represents a severe pyogenic infection of the epidural space. Clinical signs of the disease are non-specific – increased body temperature, intense neck pain, neurological signs of a transverse myelopathy – and can lead to severe and permanent ne...
作者:Jean-Laurent Thibaud , Ane Uriarte ...
来源:[J].Neuromuscular Disorders(IF 3.464), 2009, Vol.19 (11), pp.788-796Elsevier
摘要:Abstract(#br)Dogs affected with Golden Retriever Muscular Dystrophy (GRMD) exhibit striking clinical similarities with patients suffering from Duchenne muscular dystrophy (DMD), particularly gait impairments. The purpose of this study was to describe the use and reliability of ac...

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