全部文献期刊会议图书|学者科研项目
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作者:Jean-Claude Madelmont , Sébastien Tarrit ...
来源:[J].European Journal of Medicinal Chemistry(IF 3.499), 2015, Vol.92, pp.818-838Elsevier
摘要:Abstract(#br)Melanin pigment represents an attractive target to address specific treatment to melanoma cells, such as cytotoxic radionuclides. However, less than half of the patients have pigmented metastases. Hence, specific marker is required to stratify this patient popul...
作者:Jean-Claude Madelmont , Nicole Moins ...
来源:[J].European Journal of Medicinal Chemistry(IF 3.499), 2013, Vol.63, pp.840-853Elsevier
摘要:Abstract(#br)In order to develop new iodinated and fluorinated matched-pair radiotracers for Single-Photon Emission Computed Tomography (SPECT)/Positron Emission Tomography (PET) imaging and targeted radionuclide therapy of melanoma, we successfully synthesized and radiolabe...
作者:... Pierre Renard , Jean-Claude Madelmont , Emmanuelle Mounetou
来源:[J].Bioorganic & Medicinal Chemistry(IF 2.903), 2007, Vol.15 (6), pp.2368-2374Elsevier
摘要:Abstract(#br)Among other non-antibiotic properties, tetracyclines inhibit matrix metalloproteinases and are currently under study for the treatment of osteoarthritis. Quaternary ammonium conjugates of tetracyclines were synthesized by direct alkylation of the amine function at th...
作者:Jean-Claude Madelmont , Nicole Moins
来源:[J].Bioorganic & Medicinal Chemistry(IF 2.903), 2008, Vol.16 (16), pp.7671-7690Elsevier
摘要:Abstract(#br)Various iodo-acridone and acridine carboxamides have been prepared and evaluated as agents for targeted radionuclide and/or chemotherapy for melanoma, due to their structural similarity to benzamides which are known to possess specific affinity for melanin. Three of ...
作者:Jean-Claude Madelmont , Jean-Michel Chezal
来源:[J].Journal of Chromatography B(IF 2.487), 2008, Vol.875 (2), pp.411-418Elsevier
摘要:Abstract(#br)N -(2-diethylaminoethyl)-6-iodoquinoxaline-2-carbamide (ICF 01012) is a new melanoma imaging agent showing promising properties for application in internal radionuclide therapy. We developed an analytical protocol for detection of ICF 01012 in biological samples usin...
作者:... Ana Mustel , Jean-Claude Madelmont , Gérard Ledoigt
来源:[J].Advances in Biological Chemistry, 2013, Vol.3 (5), pp.485-500Airiti
摘要:Plants can respond to traumatism by synthesis and secretion of defence molecules. Wound-healing and desiccation stress of pieces of potato tuber parenchyma (Solanum tuberosum) promoted the secretion of a patatin-like phospholipase A_2, PLA_2 (EC.3.1.1.4.) that displayed cyto...

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