全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Jean-Christophe Cintrat , Feng Gao ...
来源:[J].Viruses(IF 2.509), 2018, Vol.10 (3)DOAJ
摘要:Herpes simplex virus type 2 (HSV-2) is the causative pathogen of genital herpes and is closely associated with the occurrence of cervical cancer and human immunodeficiency virus (HIV) infection. The absence of an effective vaccine and the emergence of drug resistance to comm...
作者:Jean-Christophe Cintrat , Feng Gao ...
来源:[J].Antiviral Research(IF 3.925), 2017, Vol.144, pp.311-321Elsevier
摘要:Abstract(#br)Enterovirus 71 (EV71) is one of the causative pathogens of hand, foot and mouth disease (HFMD), especially the form associated with fatal neurological disorders. Sustained outbreaks of EV71 infections remain a serious health threat worldwide. However, no antivir...
作者:Jean-Christophe Cintrat , Daniel Gillet ...
来源:[J].Antiviral Research(IF 3.925), 2018, Vol.149, pp.154-163Elsevier
摘要:Abstract(#br)Members of the family Filoviridae cause severe, often fatal disease in humans, for which there are no approved vaccines and only a few experimental drugs tested in animal models. Retro-2, a small molecule that inhibits retrograde trafficking of bacterial and plant to...
作者:Jean-Christophe Cintrat , Philippe M. Loiseau
来源:[J].Bioorganic & Medicinal Chemistry Letters(IF 2.338), 2019Elsevier
摘要:Abstract(#br)This study describes the synthesis of fluorescent probes as potential substrates for the polyamine transport system (PTS) of Leishmania donovani . A competitive radioassay was used to determine the most efficient probe. We observed that the conjugate spermine-ni...
作者:Jean-Christophe Cintrat , Errol Blart ...
来源:[J].Tetrahedron(IF 2.803), 1997, Vol.53 (22), pp.7615-7628Elsevier
摘要:Abstract(#br)α-Tributylstannylacetals derived from chiral C 2 symmetry axis diols were reacted with miscellaneous organometallic reagents to give chiral α-oxygenated organotins in high yields. The Lewis acid promoted ring opening of the these chiral α-tributylstannylacetals ...
作者:Jean-Christophe Cintrat , Florence Pillon , Bernard Rousseau
来源:[J].Tetrahedron Letters(IF 2.397), 2001, Vol.42 (30), pp.5001-5003Elsevier
摘要:Abstract(#br)A highly efficient method for labeling with deuterium is described using an acidic hydrocarbon as transfer agent. Using 9-[ 2 H ]-9-phenylfluorene as the deuterium donor, numerous organic compounds have been labeled in fair yields and good isotopic enrichment.
作者:Nicolas Faucher , Jean-Christophe Cintrat , Bernard Rousseau
来源:[J].Applied Catalysis A, General(IF 3.41), 2008, Vol.346 (1), pp.86-89Elsevier
摘要:Abstract(#br)Hydrogenolysis or deuterogenolysis of organolithium compounds is described for the first time under heterogeneous catalysis. This work establishes that the carbon–lithium bond can undergo a facile reduction reaction when catalyzed by palladium or platinum cataly...

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