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作者:... Dimitri Gilis , Jean Marc Kwasigroch , Marianne Rooman
来源:[J].Journal of Molecular Biology(IF 3.905), 2003, Vol.330 (5), pp.1215-1225
摘要:Abstract(#br)Three-dimensional domain swapping occurs when two or more identical proteins exchange identical parts of their structure to generate an oligomeric unit. It affects proteins with diverse sequences and structures, and is expected to play important roles in evoluti...
作者:Jean Marc Kwasigroch , Philippe Bogaerts
来源:[J].Physical Biology(IF 2.62), 2009, Vol.6 (1)
摘要:The time evolution of gene expression across the developmental stages of the host organism can be inferred from appropriate DNA microarray time series. Modeling this evolution aims eventually at improving the understanding and prediction of the complex phenomena that are the...
作者:... Fabian Teheux , Jean Marc Kwasigroch , Marianne Rooman
来源:[J].Proteins: Structure, Function, and Bioinformatics(IF 3.337), 2014, Vol.82 (9), pp.1734-1746
摘要:ABSTRACT(#br)The identification of immunogenic regions on the surface of antigens, which are able to stimulate an immune response, is a major challenge for the design of new vaccines. Computational immunology aims at predicting such regions—in particular B‐cell epitopes...
作者:Jean Marc Kwasigroch , Marianne Rooman
来源:[J].Bioinformatics(IF 5.323), 2006, Vol.22 (14), pp.1800-1802
摘要:Summary: Prelude&Fugue are bioinformatics tools aiming at predicting the local 3D structure of a protein from its amino acid sequence in terms of seven backbone torsion angle domains, using database-derived potentials. Prelude&Fugue computes all lowest free energy conf...
作者:Jean Marc Kwasigroch , Philippe Bogaerts
来源:[J].IFAC Proceedings Volumes, 2008, Vol.41 (2), pp.14594-14599
摘要:Abstract(#br)The evolution of the gene expression pattern of Drosophila , from the embryonic to adult development phases, was studied on the basis of a microarray time series involving the expression levels of 4028 genes over 67 time-points. The genes presenting a similar tempora...

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