全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Jason A. Konner , Kathleen N. Moore ...
来源:[J].Gynecologic Oncology(IF 3.929), 2017Elsevier
摘要:Abstract(#br)Purpose(#br)To characterize folate receptor alpha (FRα) expression in archival and fresh biopsy tumor samples from relapsed ovarian cancer patients.(#br)Methods(#br)Patients with ovarian tumors amenable to biopsy were eligible to enroll. Eligibility included a m...
作者:Jason A. Konner , Roisin E. O'Cearbhaill ...
来源:[J].Gynecologic Oncology(IF 3.929), 2019Elsevier
摘要:Abstract(#br)Objectives(#br)Immune checkpoint inhibitors (ICIs) have modest activity in ovarian cancer (OC), yet little is known about their effects on subsequent treatment. Preclinical studies suggest immunotherapy may enhance response to chemotherapy. We sought to evaluate...
作者:... Naga Vara Kishore Pillarsetty , Jason A. Konner , Thomas Reiner
来源:[J].EJNMMI Research, 2018, Vol.8 (1), pp.1-10Springer
摘要:Abstract(#br) Background(#br)The folate receptor α (FRα)-targeting antibody-drug conjugate (ADC), IMGN853, shows great antitumor activity against FRα-expressing tumors in vivo, but patient selection and consequently therapy outcome are based on immunohistochemistry. The aim ...
作者:... Mario M. Leitao , Jason A. Konner , Carol A. Aghajanian
来源:[J].Gynecologic Oncology(IF 3.929), 2015, Vol.139 (2), pp.236-241Elsevier
摘要:Abstract(#br)Objective(#br)Ovarian clear cell carcinomas (OCCCs) are rare, and uncertainty exists as to the optimal treatment paradigm and validity of the FIGO staging system, especially in early-stage disease.(#br)Methods(#br)We performed a retrospective cohort study of all OCCC...
作者:Jason A. Konner , Maura N. Dickler
来源:[J].Gynecologic Oncology(IF 3.929), 2017, Vol.147 (3), pp.621-625Elsevier
摘要:Abstract(#br)Objective(#br)Bevacizumab, a monoclonal antibody to VEGF, has shown efficacy in ovarian, cervical and endometrial cancer in addition to several other solid tumors. Serious side effects include hypertension, proteinuria, bowel perforation, and thrombosis. We tested th...
作者:Jason A. Konner , Richard R. Barakat ...
来源:[J].Gynecologic Oncology(IF 3.929), 2012, Vol.124 (1), pp.59-62Elsevier
摘要:Abstract(#br)Objective(#br)Adjuvant intraperitoneal (IP) platinum-based chemotherapy has been shown to improve outcome for patients with advanced ovarian cancer. We hypothesize that patients who have received adjuvant IP chemotherapy more commonly recur first at extraperitoneal s...
作者:Jason A. Konner , Lloyd J. Old
来源:[J].Nuclear Medicine and Biology(IF 2.517), 2007, Vol.35 (3), pp.343-351Elsevier
摘要:Abstract(#br)Introduction(#br)The in vitro and in vivo behavior of the radiolabeled monoclonal antibody MORAb-003 was investigated as a prelude to a clinical trial.(#br)Methods(#br)The cellular retention of 111 In- and 131 I-labeled MORAb-003 was investigated using IGROV1 an...
作者:Jason A. Konner , William P. Tew ...
来源:[J].International Journal of Gynecological Cancer(IF 1.941), 2016, Vol.26 (2), pp.255-260Wolters Kluwer
摘要:OBJECTIVE: The aim of the study was to evaluate the activity and tolerability of iniparib monotherapy in women with BRCA1 or BRCA2-associated advanced epithelial ovarian, fallopian tube, or primary peritoneal cancer. METHODS AND MATERIALS: Eligible patients had advanced epit...

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