全部文献期刊会议图书|学者科研项目
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作者:Janne Lehtiö , Matthias Löhr
来源:[J].Metabolomics(IF 4.433), 2017, Vol.13 (5)
摘要:Pancreatic ductal adenocarcinoma (PDAC) is the fifth most common cause of cancer-related death in Europe with a 5-year survival rate of <5%. Chronic pancreatitis (CP) is a risk factor for PDAC development, but in the majority of cases malignancy is discovered too late for curativ...
作者:Janne Lehtiö , Barbro Ek-Rylander
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)
摘要:Tartrate-resistant acid phosphatase (TRAP/ ACP5 ), a metalloenzyme that is characteristic for its expression in activated osteoclasts and in macrophages, has recently gained considerable focus as a driver of metastasis and was associated with clinically relevant parameters of can...
作者:Janne Lehtiö , Pål Stenmark
来源:[J].Journal of Molecular Biology(IF 3.905), 2018, Vol.430 (3), pp.348-362
摘要:Abstract(#br)Proteolysis plays an important role in mitochondrial biogenesis, from the processing of newly imported precursor proteins to the degradation of mitochondrial targeting peptides. Disruption of peptide degradation activity in yeast, plant and mammalian mitochondri...
作者:... Anders Höög , Janne Lehtiö , Catharina Larsson
来源:[J].Molecular and Cellular Endocrinology(IF 4.039), 2018, Vol.470, pp.84-95
摘要:Abstract(#br)Context(#br)Parathyroid adenomas may be composed of chief cells (conventional or water-clear), oxyphilic cells or a mixture of both cells. The molecular background is rarely studied.(#br)Objective(#br)To molecularly characterize parathyroid adenomas of different...
作者:... Oliver Frings , Erik Fredlund , Janne Lehtiö
来源:[J].Molecular Cell(IF 15.28), 2019, Vol.73 (1), pp.166-182.e7
摘要:Summary(#br)Subcellular localization is a main determinant of protein function; however, a global view of cellular proteome organization remains relatively unexplored. We have developed a robust mass spectrometry-based analysis pipeline to generate a proteome-wide view of subcell...
作者:... Marta Carroni , Janne Lehtiö , Annika Scheynius
来源:[J].Scientific Reports(IF 2.927), 2018, Vol.8 (1), pp.1-11
摘要:Abstract Malassezia sympodialis is a dominant commensal fungi in the human skin mycobiome but is also associated with common skin disorders including atopic eczema (AE). M. sympodialis releases extracellular vesicles, designated MalaEx, which are carriers of small RNAs and allerg...
作者:Janne Lehtiö , Liqun He ...
来源:[J].Scientific Reports(IF 2.927), 2017, Vol.7 (1), pp.1-13
摘要:Abstract Paladin (Pald1, mKIAA1274 or x99384 was identified in screens for vascular-specific genes and is a putative phosphatase. Paladin has also been proposed to be involved in various biological processes such as insulin signaling, innate immunity and neural crest migration. T...
作者:... Catharina Larsson , Janne Lehtiö , Anders Höög
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.10 (5)
摘要:Cystic papillary thyroid carcinoma (cPTC) is a subgroup of PTC presenting a diagnostic challenge at fine needle aspiration biopsy (FNAB). To further investigate this entity we aimed to characterize protein profiles of cyst fluids from cPTC and benign thyroid cystic lesions. In to...
作者:Janne Lehtiö , Matthew J. A. Wood ...
来源:[J].Scientific Reports(IF 2.927), 2018, Vol.8 (1), pp.1-12
摘要:Abstract Extracellular vesicles (EVs) mediate cell-to-cell communication by delivering or displaying macromolecules to their recipient cells. While certain broad-spectrum EV effects reflect their protein cargo composition, others have been attributed to individual EV-loaded ...

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