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作者:... Mark Blamire , Edward Tarte , James Fawcett
来源:[J].Sensors & Actuators: A. Physical(IF 1.841), 2008, Vol.147 (2), pp.456-463
摘要:Abstract(#br)Mechanical guidance is one way in which regenerating axons can be directed towards an appropriate target. In this paper, we present the design and fabrication process of a three-dimensional (3D) device comprising a bundle of parallel micro-channels, which can be...
作者:... D.Nora Abrous , James Fawcett , Stephen B Dunnett
来源:[J].Cell Transplantation(IF 4.422), 1995, Vol.4 (2), pp.173-200
摘要:Abstract(#br)The intracerebral transplantation of embryonic dopaminergic nigral neurons, although relatively successful, leads to a fairly low yield of surviving cells. Many factors may influence the viability of dopaminergic grafts and one of these is the preparation of the...
作者:Richard Eva , James Fawcett
来源:[J].Current Opinion in Neurobiology(IF 7.335), 2014, Vol.27, pp.179-185
摘要:Adult corticospinal tract axons do not regenerate because they have low intrinsic growth ability, and are exposed to inhibitory molecules after injury. PNS axons have a better regenerative capacity, mediated in part by integrins (extracellular matrix receptors). These are subject...
作者:James Fawcett , Koichi Ichimura ...
来源:[J].Journal of Neuroscience Methods(IF 2.114), 2008, Vol.176 (2), pp.192-199
摘要:Abstract(#br)A growing body of evidence suggests that glioma stem-like cells are more representative of their parent tumours when cultured under defined serum-free conditions with the mitogens epidermal growth factor (EGF) and fibroblast growth factor (FGF). However, culturing th...
作者:James Fawcett , Charles Streuli ...
来源:[J].Developmental Biology(IF 3.868), 1997, Vol.185 (2), pp.215-228
摘要:Abstract(#br)Myelination of the peripheral nervous system (PNS) requires the migration of Schwann cells during both development and regeneration. We have characterized the expression pattern of Schwann cell integrins and analyzed their role in migration on different ECM subs...
作者:James Fawcett , Josef A. Kas ...
来源:[J].Biophysical Journal(IF 3.668), 2009, Vol.96 (3), pp.196a-196a
作者:James Fawcett , Robin J.M. Franklin ...
来源:[J].Journal of Biomechanics(IF 2.716), 2010
摘要:Abstract(#br)The mechanical properties of tissues are increasingly recognized as important cues for cell physiology and pathology. Nevertheless, there is a sparsity of quantitative, high-resolution data on mechanical properties of specific tissues. This is especially true fo...
作者:... João B. Relvas , James Fawcett , Charles ffrench-Constant
来源:[J].Molecular and Cellular Neuroscience(IF 3.837), 2001, Vol.18 (1), pp.108-118
摘要:Abstract(#br)To examine the role of the extracellular matrix in regulating astrocyte behavior we previously characterized αv integrin expression on postnatal astrocytes in vitro and found that they express αvβ5 and αvβ8. Here we show that differentiation of immature cel...
作者:... D. Nora Abrous , James Fawcett , Stephen B. Dunnett
来源:[J].Cell Transplantation(IF 4.422), 1995, Vol.4
摘要:The intracerebral transplantation of embryonic dopaminergic nigral neurons, although relatively successful, leads to a fairly low yield of surviving cells. Many factors may influence the viability of dopaminergic grafts and one of these is the preparation of the tissue prior to t...
作者:... Jan M. Schwab , James Fawcett , Kevin K. Wang
来源:[J].Spinal Cord(IF 1.899), 2019, Vol.57 (12), pp.819-831
摘要:Abstract(#br)Study design(#br)This is a narrative review of the literature on neurochemical biomarkers in spinal cord injury (SCI). Objectives(#br)The objective was to summarize the literature on neurochemical biomarkers in SCI and describe their use in facilitating clinical tria...

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