全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:J A Verhaar , M R Bernsen
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.36, pp.218-230European Cells and Materials (eCM)
摘要:Mesenchymal stem cells (MSCs) represent a promising biological therapeutic option as an osteoarthritis (OA)-modifying treatment. MSCs secrete factors that can counteract inflammatory and catabolic processes and attract endogenous repair cells. The effects of intra-articular ...
作者:J A Verhaar , E M van Lieshout ...
来源:[J].Eur Cell Mater(IF 4.558), 2015, Vol.29, pp.141-154European Cells and Materials (eCM)
摘要:Regeneration of load-bearing segmental bone defects is a major challenge in trauma and orthopaedic surgery. The ideal bone graft substitute is a biomaterial that provides immediate mechanical stability, while stimulating bone regeneration to completely bridge defects over a ...
作者:J A Verhaar , S Clockaerts ...
来源:[J].Eur Cell Mater(IF 4.558), 2015, Vol.30, pp.303-314European Cells and Materials (eCM)
摘要:Cartilage repair by bone marrow derived mesenchymal stem cells (MSCs) can be influenced by inflammation in the knee. Next to synovium, the infrapatellar fat pad (IPFP) has been described as a source for inflammatory factors. Here, we investigated whether factors secreted by the I...
作者:J A Verhaar , M R Bernsen ...
来源:[J].Eur Cell Mater(IF 4.558), 2017, Vol.33, pp.43-58European Cells and Materials (eCM)
摘要:Bone marrow derived mesenchymal stem cells (MSCs) have immunomodulatory and trophic capacities. For therapeutic application in local chronic inflammatory diseases, MSCs, preferably of allogeneic origin, have to retain immunomodulatory properties. This might be achieved by encapsu...

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