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作者:... Eran Halperin , Eilon Shani , Itay Mayrose
来源:[J].Journal of Molecular Biology(IF 3.905), 2018, Vol.430 (15), pp.2184-2195
摘要:Abstract(#br)The development of the CRISPR–Cas9 system in recent years has made eukaryotic genome editing, and specifically gene knockout for reverse genetics, a simple and effective task. The system is directed to a genomic target site by a programmed single-guide RNA (sgRN...
作者:Itay Mayrose , Mario Fernández-Mazuecos ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.9 (1)
摘要:Chromosome evolution has been demonstrated to have profound effects on diversification rates and speciation in angiosperms. While polyploidy has predated some major radiations in plants, it has also been related to decreased diversification rates. There has been comparatively lit...
作者:Itay Mayrose , Dan Halperin ...
来源:[J].Molecular Immunology(IF 2.645), 2007, Vol.45 (12), pp.3477-3489
摘要:Abstract(#br)Characterizing B-cell epitopes is a fundamental step for understanding the immunological basis of bio-recognition. To date, epitope analyses have either been based on limited structural data, or sequence data alone. In this study, our null hypothesis was that th...
作者:Nimrod D. Rubinstein , Itay Mayrose , Tal Pupko
来源:[J].Molecular Immunology(IF 2.645), 2008, Vol.46 (5), pp.840-847
摘要:Abstract(#br)The immune activity of an antibody is directed against a specific region on its target antigen known as the epitope. Numerous immunodetection and immunotheraputics applications are based on the ability of antibodies to recognize epitopes. The detection of immunogenic...
作者:Itay Mayrose , Ray Ming ...
来源:[J].PLoS Biology(IF 11.452), 2014, Vol.12 (7)
摘要:Sexual reproduction is an ancient feature of life on earth, and the familiar X and Y chromosomes in humans and other model species have led to the impression that sex determination mechanisms are old and conserved. In fact, males and females are determined by diverse mechanisms t...

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