全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Ioannis Koutsounas , Adamantia Zizi-Serbetzoglou ...
来源:[J].BMC Gastroenterology(IF 2.11), 2015, Vol.15 (1)Springer
摘要:Abstract(#br) Background(#br)Histone deacetylases (HDACs) have been associated with malignant tumor development and progression in humans. HDAC inhibitors (HDACIs) are currently being explored as anti-cancer agents in clinical trials. The present study aimed to evaluate the ...
作者:Ioannis Koutsounas , Stamatios Theocharis ...
来源:[J].Expert Opinion on Drug Metabolism & Toxicology(IF 2.944), 2015, Vol.11 (4), pp.523-532Taylor & Francis
摘要:Introduction: (#br) Farnesoid x receptor (FXR) belongs to the group of nuclear receptors (NRs), which regulate the expression of various genes by binding to DNA either as a monomer or a heterodimer with retinoid x receptor.(#br) Areas covered: (#br) FXR affects several metabolic ...
作者:Ioannis Koutsounas , Constantinos Giaginis ...
来源:[J].Pancreas(IF 2.953), 2015, Vol.44 (7), pp.1134-1140Wolters Kluwer
摘要:OBJECTIVES: Pregnane X receptor (PXR) has been involved in human malignancy, either by directly affecting carcinogenesis or by inducing drug-drug interactions and chemotherapy resistance. The present study aimed to assess the clinical significance of PXR in pancreatic adenoc...
作者:Ioannis Koutsounas , Garyfallia Kaltsa ...
来源:[J].世界肝病学杂志(电子版)(英文版), 2015, (20), pp.2264-2273
摘要:Bacterial translocation(BT) refers to the passage of viable bacteria or bacterial products from the intestinal lumen, through the intestinal epithelium, into the systemic circulation and extraintestinal locations. The three principal mechanisms that are thought to be involved in ...
作者:Ioannis Koutsounas , Constantinos Giaginis , Stamatios Theocharis
来源:[J].World Journal of Gastroenterology(IF 2.547), 2013, (08), pp.1173-1181CNKI
摘要:Pancreatic cancer,although not very frequent,has an exceptionally high mortality rate,making it one of the most common causes of cancer mortality in developed countries.Pancreatic cancer is difficult to diagnose,allowing few patients to have the necessary treatment at a rela...
被引频次:-下载频次:21
作者:Ioannis Koutsounas , Constantinos Giaginis ...
来源:[J].World Journal of Gastroenterology(IF 2.547), 2013, (06), pp.813-828CNKI
摘要:Pancreatic cancer is one of the most aggressive human cancers,with more than 200 000 deaths worldwide every year.Despite recent efforts,conventional treatment approaches,such as surgery and classic chemotherapy,have only slightly improved patient outcomes.More effective and well-...
被引频次:3下载频次:14
作者:Ioannis Koutsounas , Emmanouil Pyleris ...
来源:[J].Case Reports in Gastroenterology, 2012, Vol.6 (3), pp.790-796DOAJ
摘要:Inflammatory bowel diseases (IBDs) are diseases that occur primarily in adolescence and early adult life. A second peak of IBD incidence occurs at the age of 50–80 years, while reports of first diagnosis after the age of 80 years are extremely rare. It is difficult to establ...
作者:Ioannis Koutsounas , Stamatios Theocharis ...
来源:[J].Expert Opinion on Drug Metabolism & Toxicology(IF 2.944), 2015, Vol.11 (4), pp.523-532Informa Healthcare
摘要:Introduction: Farnesoid x receptor (FXR) belongs to the group of nuclear receptors (NRs), which regulate the expression of various genes by binding to DNA either as a monomer or a heterodimer with retinoid x receptor. Areas covered: FXR affects several metabolic pathways through ...
作者:Ioannis Koutsounas , Stamatios Theocharis ...
来源:[J].Current Drug Metabolism(IF 4.405), 2013, Vol.14 (3), pp.341-350Bentham
摘要:Pregnane X Receptor (PXR), a member of the nuclear receptor (NR) superfamily, is expressed in liver and intestine, as also in other tissues and cells. PXR is activated by a wide variety of endobiotics, dietary compounds and pharmaceuticals. This nuclear receptor serves as a maste...
作者:Ioannis Koutsounas , Emmanouil Pyleris
来源:[J].Arab Journal of Gastroenterology, 2015, Vol.16 (2), pp.72-75Elsevier
摘要:Abstract(#br)Invasive aspergillosis is a life-threatening, opportunistic fungal infection that mainly affects immunocompromised patients, particularly those receiving immunosuppressive therapy or high-dose corticosteroids. The most common portal of entry in aspergillosis is the l...

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