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作者:Ioannis A. Vlachogiannis , Dimitrios Gatos ...
来源:[J].Amino Acids(IF 3.914), 2017, Vol.49 (5), pp.995-1004
摘要:Chloramphenicol peptides were recently established as useful tools for probing nascent polypeptide chain interaction with the ribosome, either biochemically, or structurally. Here, we present a new 10mer chloramphenicol peptide, which exerts a dual inhibition effect on the riboso...
作者:Ioannis A. Vlachogiannis , Georgios E. Papadopoulos ...
来源:[J].Antibiotics, 2016, Vol.5 (2)
摘要:Chloramphenicol (CAM) is the D-threo isomer of a small molecule, consisting of a p-nitrobenzene ring connected to a dichloroacetyl tail through a 2-amino-1,3-propanediol moiety. CAM displays a broad-spectrum bacteriostatic activity by specifically inhibiting the bacterial protein...
作者:Ioannis A. Vlachogiannis , Rebecca E. K. MacPherson
来源:[J].International Journal of Molecular Sciences(IF 2.464), 2018, Vol.19 (5)
摘要:Skeletal muscle is a major insulin-target tissue and plays an important role in glucose homeostasis. Insulin action in muscle activates the phosphatidylinositol-3 kinase (PI3K)/Akt signaling pathway causing the translocation of intracellularly stored GLUT4 glucose transporters to...
作者:Ioannis A. Vlachogiannis , Georgios E. Papadopoulos ...
来源:[J].Antibiotics, 2016, Vol.5 (2)
摘要:Chloramphenicol (CAM) is the D-threo isomer of a small molecule, consisting of a p-nitrobenzene ring connected to a dichloroacetyl tail through a 2-amino-1,3-propanediol moiety. CAM displays a broad-spectrum bacteriostatic activity by specifically inhibiting the bacterial protein...

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