全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Huixiao Hong , Zhaoxian Zhou ...
来源:[J].BMC Bioinformatics(IF 3.024), 2017, Vol.18 (14)Springer
摘要:Multi-label classification of data remains to be a challenging problem. Because of the complexity of the data, it is sometimes difficult to infer information about classes that are not mutually exclusive. For medical data, patients could have symptoms of multiple different diseas...
作者:Huixiao Hong , Joshua Xu ...
来源:[J].Science China Life Sciences(IF 2.024), 2019, Vol.62 (7), pp.895-904Springer
摘要:Abstract(#br)High-throughput next generation sequencing (NGS) is a shotgun approach applied in a parallel fashion by which the genome is fragmented and sequenced through small pieces and then analyzed either by aligning to a known reference genome or by de novo assembly with...
作者:Huixiao Hong , Weida Tong
来源:[J].BMC Bioinformatics(IF 3.024), 2016, Vol.17 (1)Springer
摘要:Abstract(#br) Background(#br)Next-generation sequencing (NGS) technologies have provided researchers with vast possibilities in various biological and biomedical research areas. Efficient data mining strategies are in high demand for large scale comparative and evolutional studie...
作者:... William Mattes , Donna Mendrick , Huixiao Hong
来源:[J].BMC Bioinformatics(IF 3.024), 2015, Vol.16 (13)Springer
摘要:Abstract(#br) Background(#br)As the major histocompatibility complex (MHC), human leukocyte antigens (HLAs) are one of the most polymorphic genes in humans. Patients carrying certain HLA alleles may develop adverse drug reactions (ADRs) after taking specific drugs. Peptides play ...
作者:HuiXiao Hong , WenQian Zhang ...
来源:[J].Science China Life Sciences(IF 2.024), 2013, Vol.56 (2), pp.110-118Springer
摘要:Abstract(#br)Realizing personalized medicine requires integrating diverse data types with bioinformatics. The most vital data are genomic information for individuals that are from advanced next-generation sequencing (NGS) technologies at present. The technologies continue to adva...
作者:HuiXiao Hong , ZhenQiang Su ...
来源:[J].Science China Life Sciences(IF 2.024), 2013, Vol.56 (2), pp.119-124Springer
摘要:Abstract(#br)Abacavir is an effective nucleoside analog reverse transcriptase inhibitor used to treat human immunodeficiency virus (HIV) infected patients. Its main side effect is hypersensitivity reaction (HSR). The incidence of the HSR is associated with ethnicity among patient...
作者:Huixiao Hong , Lei Xu ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.7 (9)DOAJ
摘要:During the last several years, high-density genotyping SNP arrays have facilitated genome-wide association studies (GWAS) that successfully identified common genetic variants associated with a variety of phenotypes. However, each of the identified genetic variants only explains a...

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