全部文献期刊会议图书|学者科研项目
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作者:Huaying Wen , Liang Gu ...
来源:[J].Journal of Nanobiotechnology, 2017, Vol.15 (1)
摘要:Chemotherapeutic drugs used for cancer therapy frequently encounter multiple-drug resistance (MDR). Nanoscale carriers that can target tumors to accumulate and release drugs intracellularly have the greatest potential for overcoming MDR. Glucose transporter-1 (GLUT-1) and glutath...
作者:Huaying Wen , Siyan Liao ...
来源:[J].Biochemical Pharmacology(IF 4.576), 2017, Vol.135, pp.35-49
摘要:Abstract(#br)Expression of CDC28 protein kinase regulatory subunit 1 ( Cks1 ), an adaptor for cyclin-dependent kinases, is tightly regulated at transcriptional and posttranslational levels. Increased expression of Cks1 has been documented to be attributable to cancer progression,...
作者:Huaying Wen , Wenwen Shi ...
来源:[J].Journal of Nanobiotechnology, 2020, Vol.18 (1), pp.220-233
摘要:Abstract(#br)Chemotherapeutic drugs frequently encounter multidrug resistance. ATP from mitochondria helps overexpression of drug efflux pumps to induce multidrug resistance, so mitochondrial delivery as a means of “repurposing’’ chemotherapeutic drugs currently used in...

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