全部文献期刊会议图书|学者科研项目
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作者:Hongdi Cao , Ping Wen ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (12)DOAJ
摘要:Although a large number of drugs have been used to treat chronic hepatitis C (CHC), there still remains a great challenge to treat maintenance hemodialysis (MHD) patients with chronic hepatitis C. To clarify the immunnoloregulation of double filtration plasmapheresis (DFPP) in MH...
作者:Hongdi Cao , Hong Ye ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.9 (12)DOAJ
摘要:Chronic inflammation is highly prevalent in maintenance hemodialysis (MHD) patients, and it has been shown to be a strong predictor of morbidity and mortality. Mitochondrial DNA (mtDNA) released into circulation after cell damage can promote inflammation in patients and anim...
作者:Hongdi Cao , Weifang Su
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (8)DOAJ
摘要:Albuminuria contributes to the progression of tubulointerstitial fibrosis. Although it has been demonstrated that ongoing albuminuria leads to tubular injury manifested by the overexpression of numerous proinflammatory cytokines, the mechanism remains largely unknown. In this stu...
作者:Hongdi Cao , Weichun He ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.9 (10)DOAJ
摘要:BACKGROUND: MicroRNAs (miRNAs) are small ribonucleotides regulating gene expression. MicroRNAs are present in the blood in a remarkably stable form and have emerged as potential diagnostic markers in patients with cardiovascular disease. Our study aimed to assess circulating miR-...
作者:Hongdi Cao , Weichun He ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.7 (6)DOAJ
摘要:Inflammation is a pathologic feature of hyperuricemia in clinical settings. However, the underlying mechanism remains unknown. Here, infiltration of T cells and macrophages were significantly increased in hyperuricemia mice kidneys. This infiltration of inflammatory cells wa...
作者:Hongdi Cao , Li Fang ...
来源:[J].Cellular Physiology and Biochemistry(IF 3.415), 2014, Vol.34 (4), pp.1063-1074DOAJ
摘要:Background: Fibroblast activation is one of the most important mechanisms for Angiotensin II (Ang II) in promoting renal fibrosis. Transcription factor Ets-1 is recognized to play a key role in kidney diseases. However, the role and mechanisms of Ets-1 in Ang-II induced fibr...
作者:Hongdi Cao , Li Fang ...
来源:[J].Experimental Cell Research(IF 3.557), 2014, Vol.322 (2), pp.302-312Elsevier
摘要:Abstract(#br)Objectives(#br)Vascular calcification is highly prevalent in patients with chronic kidney disease (CKD) and contributes to increased risk of cardiovascular disease and mortality. Accumulated evidences suggested that vascular smooth muscle cells (VSMCs) to osteob...
作者:Hongdi Cao , Junwei Yang ...
来源:[J].Experimental Cell Research(IF 3.557), 2013, Vol.319 (14), pp.2254-2265Elsevier
摘要:Abstract(#br)Specificity protein 1 (Sp1), a ubiquitously expressed transcription factor, plays a potential pathogenic role for fibrotic disease in many organs by regulating the expression of several fibrosis-related genes, however, its role in kidney fibrosis and the mechani...
作者:Hongdi Cao , Jining Wu ...
来源:[J].Diabetes/Metabolism Research and Reviews(IF 2.968), 2019, Vol.35 (4), pp.n/a-n/aWiley
摘要:Abstract(#br)Background(#br)Mitochondrial dysfunction and chronic sterile inflammation are common features of type 2 diabetes. Therefore, we aimed to investigate whether mitochondrial DNA (mtDNA) could be a biomarker implicated in the progression of type 2 diabetes and diabe...

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