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作者:Buchmann Jan P. , Holmes Edward C.
来源:[J].Microbiology and Molecular Biology Reviews(IF 16.417), 2015, Vol.79 (4), pp.403-418
摘要:SUMMARY Why some viruses are enveloped while others lack an outer lipid bilayer is a major question in viral evolution but one that has received relatively little attention. The viral envelope serves several functions, including protecting the RNA or DNA molecule(s), evading reco...
作者:Holmes Edward C. , Rambaut Andrew
来源:[J].Philosophical Transactions of the Royal Society B: Biological Sciences(IF 6.23), 2004, Vol.359 (1447), pp.1059-1065
摘要:The recent appearance of severe acute respiratory syndrome coronavirus (SARS–CoV) highlights the continual threat to human health posed by emerging viruses. However, the central processes in the evolution of emerging viruses are unclear, particularly the selection pressures...
作者:... Duchêêne Sebastian , Holmes Edward C. , Ho Simon Y.W.
来源:[J].Molecular Biology and Evolution(IF 10.353), 2015, Vol.32 (11), pp.2986-2995
摘要:Molecular clock models are commonly used to estimate evolutionary rates and timescales from nucleotide sequences. The goal of these models is to account for rate variation among lineages, such that they are assumed to be adequate descriptions of the processes that generated the d...
作者:... Duckworth Janine A. , Strive Tanja , Holmes Edward C.
来源:[J].Journal of Virology(IF 5.076), 2015, Vol.89 (23), pp.12217-12220
摘要:To resolve the evolutionary history of rabbit hemorrhagic disease virus (RHDV), we performed a genomic analysis of the viral stocks imported and released as a biocontrol measure in Australia, as well as a global phylogenetic analysis. Importantly, conflicts were identified betwee...
作者:Geoghegan Jemma L. , Senior Alistair M. , Holmes Edward C.
来源:[J].Proceedings of the Royal Society B: Biological Sciences(IF 5.683), 2016, Vol.283 (1837), pp.20160727-20160727
摘要:Emerging diseases are a major challenge to public health. Revealing the evolutionary processes that allow novel pathogens to adapt to new hosts, also the potential barriers to host adaptation, is central to understanding the drivers of disease emergence. In particular, it is...

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