全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Peter Schraml , Holger Moch , Niko Beerenwinkel
来源:[J].BMC Bioinformatics(IF 3.024), 2017, Vol.18 (1)Springer
摘要:Next-generation sequencing of matched tumor and normal biopsy pairs has become a technology of paramount importance for precision cancer treatment. Sequencing costs have dropped tremendously, allowing the sequencing of the whole exome of tumors for just a fraction of the total tr...
作者:Holger Moch , Aurelia Noske
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:BRCA1/2-deficient ovarian carcinomas are recognized as target for Poly (ADP-ribose) polymerase (PARP) inhibitors. BRCA1 and BRCA2 proteins are involved in homologous recombination repair of double-strand DNA breaks. The relevance of other homologous recombination repair proteins,...
作者:Holger Moch , Markus Rechsteiner ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:Endometrioid adenocarcinoma of the uterus and ovarian endometrioid carcinoma share many morphological and molecular features. Differentiation between simultaneous primary carcinomas and ovarian metastases of an endometrial cancer may be very challenging but is essential for progn...
作者:... David Holzmann , Holger Moch , Kristian Ikenberg
来源:[J].European Archives of Oto-Rhino-Laryngology(IF 1.458), 2017, Vol.274 (9), pp.3503-3512Springer
摘要:The aim of this study was to analyze the role of Ki-67, p53, and the “aberrant p53 pattern” in squamous cell carcinomas of the nasal vestibule. Patients between 1995 and 2014 were included. Baseline characteristics and outcome were analyzed with respect to immunohistochemica...
作者:... Mark A Rubin , Holger Moch , Peter Schraml
来源:[J].BMC Genomics(IF 4.397), 2015, Vol.16 (1)Springer
摘要:Abstract(#br) Background(#br)Chimeric read-through RNAs are transcripts originating from two directly adjacent genes (<10 kb) on the same DNA strand. Although they are found in next-generation whole transcriptome sequencing (RNA-Seq) data on a regular basis, investigating them fu...
作者:... Manuela Schmidinger , Holger Moch , Peter Schraml
来源:[J].BMC Cancer(IF 3.333), 2016, Vol.16 (1)Springer
摘要:Abstract(#br) Background(#br)The VHL protein (pVHL) is a multiadaptor protein that interacts with more than 30 different binding partners involved in many oncogenic processes. About 70 % of clear cell renal cell carcinoma (ccRCC) have VHL mutations with varying impact on pVH...
作者:Holger Moch , Gerd Stuckmann ...
来源:[J].BMC Nephrology(IF 1.644), 2018, Vol.19 (1), pp.1-5DOAJ
摘要:Abstract Background Epithelioid angiomyolipoma is defined as potentially malignant mesenchymal neoplasm, characterized by proliferating epithelioid cells, whereas classic angiomyolipoma, composed of fat, smooth muscle cells and dysmorphic vessels, is defined as a potentially beni...

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