全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Sungmin Cho , Ho Jeong Kwon , Peter Karuso
来源:[J].Proteome Science(IF 2.42), 2016, Vol.15 (1)Springer
摘要:Daptomycin is a recently introduced, last-resort antibiotic that displays a unique mode of action against Gram-positive bacteria that is not fully understood. Several bacterial targets have been proposed but no human binding partner is known.
作者:Ho Jeong Kwon , Sung Joon Hong
来源:[J].BMC Cancer(IF 3.333), 2015, Vol.15 (1)Springer
摘要:Abstract(#br) Background(#br)Epigenetic modifications play a critical role in the regulation of all DNA-based processes, such as transcription, repair, and replication. Inappropriate histone modifications can result in dysregulation of cell growth, leading to neoplastic transform...
作者:... Yoon Sun Cho , Hukeun Lee , Ho Jeong Kwon
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.9 (3)DOAJ
摘要:Autophagy and apoptosis are important processes that control cellular homeostasis and have been highlighted as promising targets for novel cancer therapies. Here, we identified convallatoxin (CNT), isolated from Antiaris toxicaria, as a dual inducer of autophagy and apoptosis. CN...
作者:Ho Jeong Kwon , Henrik Lindberg ...
来源:[J].Clinical and Translational Medicine, 2018, Vol.7 (1), pp.1-9Springer
摘要:Abstract(#br)We present the Cancer Moonshot clinical project located at the European center in Lund. Here, tissue and blood samples have been collected and stored in a large-scale biobank. Multiple clinical centers around the world are participating and tissue and blood samp...
作者:... Chan-Wha Kim , Ho Jeong Kwon , Yeo Joon Yoon
来源:[J].Journal of Industrial Microbiology & Biotechnology(IF 2.321), 2019, Vol.46 (8), pp.1205-1215Springer
摘要:Abstract(#br)Genomic analysis of the clavulanic acid (CA)-high-producing Streptomyces clavuligerus strains, OL13 and OR, developed through random mutagenesis revealed a frameshift mutation in the cas1 gene-encoding clavaminate synthase 1. Overexpression of the intact cas1 in S. c...
作者:... Seung-Woo Cho , Sang-Kyou Lee , Ho Jeong Kwon
来源:[J].Cancer Letters(IF 4.258), 2015, Vol.366 (1), pp.52-60Elsevier
摘要:Abstract(#br)Ubiquinol–cytochrome c reductase binding protein (UQCRB), a component of the mitochondrial complex III, has been recently implicated in angiogenesis. Targeting mitochondria to balance vascular homeostasis has been widely recognized. However, the effect of UQCRB ...
作者:... Hye Jin Jung , Deepak Bhattarai , Ho Jeong Kwon
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2015, Vol.458 (1), pp.14-20Elsevier
摘要:Abstract(#br)Hypoxia inducible factor-1 alpha (HIF-1α) plays an important role in angiogenesis and metastasis and is a promising therapeutic target for the development of anti-cancer drugs. We recently developed a new synthetic small molecule inhibitor of HIF-1α, LW6, which ...

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