全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Shangfeng Gao , Rutong Yu , Hengliang Shi
来源:[J].Molecular Neurobiology(IF 5.471), 2017, Vol.54 (7), pp.5008-5016Springer
摘要:Human glioma causes substantial morbidity and mortality worldwide. However, the molecular mechanisms underlying glioma progression are still largely unknown. COP1 (constitutively photomorphogenic 1), an E3 ubiquitin ligase, is important in cell survival, development, cell growth,...
作者:Hengliang Shi , Zhenzhen Wang ...
来源:[J].Cellular Physiology and Biochemistry(IF 3.415), 2018, Vol.50 (6), pp.2314-2328DOAJ
摘要:Background/Aims: Chronic Lymphocytic leukemia (CLL) is characterized by accumulation of cells in the G0/G1 phase of the cell cycle and resistance to apoptosis due to gene mutation or abnormal gene expression. In our previous study, constitutively photomorphogenic 1 (COP1) wa...
作者:Hengliang Shi , Chunling Fu ...
来源:[J].Journal of Cellular and Molecular Medicine(IF 4.753), 2014, Vol.18 (10), pp.2061-2070Wiley
摘要:Abstract(#br)Immunotherapy mediated by recombinant antibodies is an effective therapeutic strategy for a variety of cancers. In a previous study, we demonstrated that the fibroblast growth factor 1 ( FGF ‐1)‐specific recombinant antibody scFv1C9 arrests the cell cycle at the...
作者:Hengliang Shi , Xuejiao Liu ...
来源:[J].Cancer Letters(IF 4.258), 2018, Vol.415, pp.151-163Elsevier
摘要:Abstract(#br)The RIO (right open reading frame) protein kinases include RIOK1, RIOK2 and RIOK3. Emerging evidence has suggested an important role of RIO kinases in cancer cell proliferation, apoptosis, migration and invasion. However, the expression profile and specific roles of ...
作者:Hengliang Shi , Daxue Zheng ...
来源:[J].Biomaterials(IF 7.604), 2012, Vol.33 (18), pp.4589-4596Elsevier
摘要:Abstract(#br)Recent studies in amphiphilic cationic polymers have demonstrated their potential as gene carriers with high transfection efficiency and low cytotoxicity in the in vitro settings to deliver drug, siRNA and plasmid DNA. Yet their safety and efficacy in vivo remain to ...
作者:... Lei Wang , Hengliang Shi , Rutong Yu
来源:[J].Journal of Neuro-Oncology(IF 3.115), 2017, Vol.131 (1), pp.31-39Springer
摘要:Abstract(#br)Jab1 (Jun activation domain-binding protein 1), also known as CSN5 (COP9 signalosome subunit 5), is frequently overexpressed in several cancer types. However, the biological functions and the molecular mechanisms of the Jab1 protein in human gliomas have not bee...
作者:Hengliang Shi , Dong Lu ...
来源:[J].Cancer Letters(IF 4.258), 2014, Vol.355 (1), pp.121-129Elsevier
摘要:Abstract(#br)Protein kinase D2 (PKD2) has been demonstrated to promote tumorigenesis in many types of cancers. However, how PKD2 regulates cancer cell growth is largely unknown. In this study, we found that over-expression of PKD2 promoted glioma cell growth but down-regulation o...
作者:Hengliang Shi , Hui Gong ...
来源:[J].Journal of Neuro-Oncology(IF 3.115), 2015, Vol.124 (3), pp.357-364Springer
摘要:Abstract(#br)We previously reported that loss of Nrdp1 contributes to human glioma progression by reducing apoptosis. However, the role of Nrdp1 in glioma migration and invasion has not been investigated. Here, we report that ErbB3, a substrate of Nrdp1, is undetectable in normal...

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