全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Hee-Yoon Lee , Bora Kim ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.7 (5)DOAJ
摘要:Soluble epoxide hydrolase (sEH) in endothelial cells determines the plasma concentrations of epoxyeicosatrienoic acids (EETs), which may act as vasoactive agents to control vascular tone. We hypothesized that the regulation of sEH activity may have a therapeutic value in preventi...
作者:... Hyotcherl Ihee , Hee-Yoon Lee , Jeong-Hun Sohn
来源:[J].J. Org. Chem., 2013, Vol.78 (17), pp.8242鈥?249ACS
摘要:† Department of Chemistry, College of Natural Sciences, Chungnam National University, Daejeon 305-764, Korea ... ‡ Department of Chemistry, KAIST, Daejeon 305-701, Korea ... (Royal Society of Chemistry) ...
作者:Yoon-Jung Kim , Yeokwon Yoon , Hee-Yoon Lee
来源:[J].Tetrahedron(IF 2.803), 2013, Vol.69 (36), pp.7810-7816Elsevier
摘要:Abstract(#br)A stereoselective total synthesis of (+)-pentalenene was achieved through the tandem cycloaddition reaction of the allenyl diazo substrate prepared from (+)-citronellal. The initial intramolecular [2+3] cycloaddition reaction between the diazo functionality and the a...
作者:Hee-Yoon Lee , Hyun Seop Tae ...
来源:[J].Tetrahedron Letters(IF 2.397), 2003, Vol.44 (31), pp.5803-5806Elsevier
摘要:Abstract(#br)The first and practical total synthesis of gelastatins 1 , a novel matrix metalloproteinase inhibitor possessing antitumor activity, was accomplished in nine steps starting from Meldrum's acid.
作者:Hee-Yoon Lee , Yeokwon Yoon ...
来源:[J].Tetrahedron Letters(IF 2.397), 2008, Vol.49 (39), pp.5693-5696Elsevier
摘要:Abstract(#br)Intramolecular [2+3] cycloaddition reaction of trimethylenemethane diyls that were generated successfully from the reaction of malonate anions containing diene units with propynyl iodonium salts via alkylidene carbene intermediates produced linearly fused triquinanes...
作者:Hee-Yoon Lee , Jeong-Hun Sohn , Byoung-Mog Kwon
来源:[J].Bioorganic & Medicinal Chemistry Letters(IF 2.338), 2002, Vol.12 (12), pp.1599-1602Elsevier
摘要:Abstract(#br)The first example of tripeptide inhibitors of farnesyltransferase with sub-micromolar inhibition activity was developed based on the fact that CVFM is not a substrate for farnesyltransferase.
作者:Hee-Yoon Lee , Sejin Lee ...
来源:[J].Tetrahedron Letters(IF 2.397), 1998, Vol.39 (42), pp.7713-7716Elsevier
摘要:Abstract(#br)Tandem free radical cycloaddition reaction of the N-Aziridinylimine intermediate produced tricyclo[5.3.1.0 1,5 ]undecane skeleton stereoselectively. A total synthesis of α-cedrene was completed in three step sequence from the cyclization product.
作者:Hee-Yoon Lee , Won-Yeob Kim , Sejin Lee
来源:[J].Tetrahedron Letters(IF 2.397), 2006, Vol.48 (8), pp.1407-1410Elsevier
摘要:Abstract(#br)Linear compounds containing a ketone and diene functional groups reacted with the anion of TMS–diazomethane to produce alkylidene carbenes that underwent intramolecular cyclopropanation followed by the formation of trimethylenemethane diyls which underwent [2+3]...
作者:Hee-Yoon Lee , Mihyun An
来源:[J].Tetrahedron Letters(IF 2.397), 2003, Vol.44 (14), pp.2775-2778Elsevier
摘要:Abstract(#br)α,β-Unsaturated ketones and aldehydes were selectively reduced to the corresponding saturated carbonyl compounds by Co 2 (CO) 8 –H 2 O system. The current reducing system also offered a chemoselective reduction of less substituted unsaturated carbonyl groups.
作者:Hee-Yoon Lee , Jeong-Hun Sohn , Hyoun Young Kim
来源:[J].Tetrahedron Letters(IF 2.397), 2001, Vol.42 (9), pp.1695-1698Elsevier
摘要:Abstract(#br)The oxidopyrylium cycloaddition reaction of allenes was investigated. Contrary to other cycloaddition reactions, electron deficient allenes were not reactive at all and electron rich allenes were slightly more reactive than neutral allenes. The intermolecular cycload...

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