全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Hee Sun Kim , Jae Jun Park ...
来源:[J].BMC Gastroenterology(IF 2.11), 2017, Vol.17 (1)Springer
摘要:Limited data are available for advanced colorectal neoplasm in asymptomatic individuals aged 40–49 years. We aimed to identify risk factors and develop a simple prediction model for advanced colorectal neoplasm in these persons.
作者:Hee Sun Kim , Sun Kyung Oh
来源:[J].Tissue Engineering and Regenerative Medicine(IF 0.345), 2017, Vol.14 (4), pp.453-464Springer
摘要:Human embryonic stem cell (hESC) culture system has been changing culture conditions from conventional to xeno-free for therapeutic cell applications, and N -glycolylneuraminic acid (Neu5Gc) could be a useful indicator of xenogeneic contaminations in hESCs because human cells can...
作者:... Sungwook Chae , Hee Sun Kim , Jin Won Hyun
来源:[J].International Journal of Molecular Sciences(IF 2.464), 2011, Vol.12 (6), pp.3871DOAJ
摘要:Recently, we demonstrated that butin (7,3′,4′-trihydroxydihydroflavone) protected cells against hydrogen peroxide (H2O2)-induced apoptosis by: (1) scavenging reactive oxygen species (ROS), activating antioxidant enzymes such superoxide dismutase and catalase; (2) decreasing ...
作者:Hee Sun Kim , Dong Hyun Kim ...
来源:[J].International Journal of Molecular Sciences(IF 2.464), 2010, Vol.11 (12), pp.4916DOAJ
摘要:The objective of this study was to elucidate the cytotoxic mechanism of Compound K, with respect to the involvement of reactive oxygen species (ROS) and the mitochondrial involved apoptosis, in HT-29 human colon cancer cells. Compound K exhibited a concentration of 50% growt...
作者:Hee Sun Kim , Jae‐Ryong Kim ...
来源:[J].Journal of Cellular and Molecular Medicine(IF 4.753), 2012, Vol.16 (2), pp.273-286Wiley
摘要:Abstract(#br)Vascular calcification is prevalent in patients with chronic kidney disease and leads to increased cardiovascular morbidity and mortality. Although several reports have implicated mitochondrial dysfunction in cardiovascular disease and chronic kidney disease, li...
作者:Hee Sun Kim , Ji Duck Kim ...
来源:[J].Drug Design, Development and Therapy(IF 3.486), 2017, Vol.2017 (default), pp.1301-1313Dove
摘要:Objectives: DWP05195 is a transient receptor potential vanilloid 1 (TRPV1) antagonist developed for managing pain. The purpose of this study was to evaluate the pharmacodynamics (PD), pharmacokinetics, safety, and tolerability of DWP05195 in healthy subjects. This was a rand...
作者:Hee Sun Kim , Mei Jing Piao ...
来源:[J].International Journal of Molecular Sciences(IF 2.464), 2011, Vol.12 (6), pp.3871-3887DOAJ
摘要:Recently, we demonstrated that butin (7,3′,4′-trihydroxydihydroflavone) protected cells against hydrogen peroxide (H2O2)-induced apoptosis by: (1) scavenging reactive oxygen species (ROS), activating antioxidant enzymes such superoxide dismutase and catalase; (2) decreasing ...
作者:Hee Sun Kim , Ho-Young Yhim ...
来源:[J].Transplant Immunology(IF 1.52), 2012, Vol.27 (2-3), pp.128-137Elsevier
摘要:Abstract(#br)The effect of rosiglitazone, an agonist of peroxisome proliferator-activated receptor-γ (PPARγ), was investigated in a mouse parent-to-F1 GVHD model. Rosiglitazone inhibited mixed lymphocyte reactions, inducing enhanced apoptosis in CD4+, CD8+, and B220 + cells,...
作者:Hee Sun Kim , Il Hak Bae ...
来源:[J].European Journal of Medicinal Chemistry(IF 3.499), 2017, Vol.125, pp.87-100Elsevier
摘要:Abstract(#br)The discovery of a new series of potent hepatitis C virus (HCV) NS5A inhibitors containing biaryl sulfone or sulfate cores is reported. Structure-activity relationship (SAR) studies on inhibitors containing various substitution patterns of the sulfate or sulfone...

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