全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Minying Lu , Guopei Zheng , Zhimin He
来源:[J].Journal of Experimental & Clinical Cancer Research(IF 3.066), 2017, Vol.36 (1)Springer
摘要:The potential mechanisms regarding how methylation of microRNA(miRNA) CpG Island could regulate cancer cell chemo-resistance remains unclear. This study aims to explore the epigenetic dysregulation mechanism of miRNA-493 and the ability to modulate lung cancer cell chemotherapy r...
作者:Guopei Zheng , Cong Peng ...
来源:[J].Molecular Cancer(IF 5.134), 2015, Vol.14 (1)Springer
摘要:Abstract(#br) Background(#br)Chemoresistance is a major obstacle in successfully treating cancers, and the mechanisms responsible for drug resistance are still far from understood. Carbonic anhydrase 9 (CA9) has been shown to be upregulated in the drug-resistant tongue cance...
作者:Guopei Zheng , Xiaoting Jia ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (9)DOAJ
摘要:The polycomb group transcriptional modifier Bmi1 is often upregulated in numerous cancers and is intensely involved in normal and cancer stem cells, and importantly is as a prognostic indicator for some cancers, but its role in breast cancer remains unclear. Here, we found Bmi1 o...
作者:... Chengkun Wang , Guopei Zheng , Zhimin He
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.9 (8)DOAJ
摘要:miRNAs have been proposed to be key regulators of progression and metastasis in cancer. However, an understanding of their roles and molecular mechanisms is needed to provide deeper insights for better therapeutic opportunities. In this study we investigated the role and mechanis...
作者:Guopei Zheng , Feng Ye ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.9 (11)DOAJ
摘要:Diallyl disulfide (DADS) is one of the major volatile components of garlic oil. DADS has various biological properties, including anticancer, antiangiogenic, and antioxidant effects. However, the anticancer mechanisms of DADS in human breast cancer have not been elucidated, parti...
作者:... Yan Xiong , Guopei Zheng , Zhimin He
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.7 (12)DOAJ
摘要:We recently reported that TCRP1, a novel multidrug-resistance associated human gene, can mediate cisplatin resistance in OSCC cells. However, the molecular mechanism underlying this role of TCRP1 remained to be elucidated. In this study, by using Human Toxicology and Drug Re...
作者:... Jiang Yin , Guopei Zheng , Zhimin He
来源:[J].Journal of Experimental & Clinical Cancer Research(IF 3.066), 2018, Vol.37 (1), pp.1-14DOAJ
摘要:Abstract Background Tongue squamous cell carcinoma (TSCC) is the most common oral cancer. Neoadjuvant systemic treatment before or after surgery for advanced TSCC is considered one of the most crucial factors in reducing mortality. However, the therapeutic benefits of chemot...
作者:... Zhijie Zhang , Guopei Zheng , Zhiming He
来源:[J].Nucleosides, Nucleotides and Nucleic Acids(IF 0.713), 2018, Vol.37 (1), pp.1-19Taylor & Francis
摘要:ABSTRACT(#br) Objective : Reduction of non-specific amplification and achievement of efficient amplification of multiple gene fragments under the same reaction condition is the basic goal of PCR diagnosis; however, this is often difficult. This study was conducted to establi...
作者:... Li Ling , Kai Luo , Guopei Zheng
来源:[J].Journal of Molecular Medicine(IF 4.768), 2018, Vol.96 (8), pp.753-764Springer
摘要:Abstract(#br)Recently, emerging evidence has suggested that long noncoding RNAs (lncRNAs) have crucial roles in cancer progression. Here, we demonstrated that the lncRNA MIR4435-2HG was highly expressed in lung cancer tissues and correlated with histological grades and lymph...

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