全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Grażyna Wójcicka , Anna Jamroz-Wiśniewska ...
来源:[J].European Journal of Pharmacology(IF 2.592), 2016, Vol.789, pp.187-194Elsevier
摘要:Abstract(#br)Antidiabetic agents per se, apart from their glucose-lowering effect, can have an important impact on modifying the cardiovascular risk. The present study was undertaken to determine whether the known cardio-protective effects of metformin are linked to its pote...
作者:Grażyna Wójcicka , Anna Jamroz-Wiśniewska ...
来源:[J].Life Sciences(IF 2.555), 2010, Vol.87 (3), pp.126-132Elsevier
摘要:Abstract(#br)Aims(#br)The present study was designed to examine the effect of sulphonylureas, glimepiride (GM) and glibenclamide (GB), on paraoxonase 1 (PON1) and platelet activating factor acetylohydrolase (PAF-AH) activity in normal and streptozotocin(STZ)-induced (50 mg/kg) di...
作者:Grażyna Wójcicka , Anna Jamroz-Wiśniewska ...
来源:[J].Pharmacological Research(IF 4.346), 2010, Vol.63 (1), pp.68-76Elsevier
摘要:Abstract(#br)Hydrogen sulfide (H 2 S) is a new gasotransmitter synthesized enzymatically from l -cysteine in cytosol and is oxidized in mitochondria. In the cardiovascular system, H 2 S regulates vascular tone, inhibits atherogenesis, and protects against myocardial ischemia...
作者:Grażyna Wójcicka , Anna Jamroz-Wiśniewska ...
来源:[J].Life Sciences(IF 2.555), 2007, Vol.82 (7), pp.402-412Elsevier
摘要:Abstract(#br)We investigated if extracellular signal-regulated kinases (ERK) and oxidative stress are involved in the pathogenesis of arterial hypertension induced by chronic leptin administration in the rat. Leptin was administered at a dose of 0.25 mg/kg twice daily s.c. f...
作者:Grażyna Wójcicka , Anna Jamroz-Wiśniewska
来源:[J].Peptides(IF 2.522), 2010, Vol.31 (1), pp.155-163Elsevier
摘要:Abstract(#br)Apart from controlling energy balance, leptin, secreted by adipose tissue, is also involved in the regulation of cardiovascular function. Previous studies have demonstrated that acutely administered leptin stimulates natriuresis and vascular nitric oxide (NO) pr...
作者:Grażyna Wójcicka , Ewelina Łowicka ...
来源:[J].Biochemical Pharmacology(IF 4.576), 2008, Vol.75 (8), pp.1623-1638Elsevier
摘要:Abstract(#br)We examined the role of epidermal growth factor (EGF) receptor in the pathogenesis of leptin-induced hypertension in the rat. Leptin, administered in increasing doses (0.1–0.5 mg/kg/day) for 10 days, increased phosphorylation levels of non-receptor tyrosine kina...
作者:... Robert Palusiński , Jerzy Bełtowski , Grażyna Wójcicka
来源:[J].Atherosclerosis(IF 3.706), 2002, Vol.164 (2), pp.283-288Elsevier
摘要:Abstract(#br)Accumulating evidence indicates the involvement of sex hormones in atherogenesis. Endogenous testosterone is inversely related to the majority of risk factors for atherosclerosis and is known to be a potent immunomodulator. Recently, autoantibodies to oxidized L...
作者:Grażyna Wójcicka , Jadwiga Trzeciak
来源:[J].Peptides(IF 2.522), 2006, Vol.27 (12), pp.3234-3244Elsevier
摘要:Abstract(#br)We examined the mechanism through which leptin increases Na + , K + -ATPase activity in the rat kidney. Leptin was infused under anaesthesia into the abdominal aorta proximally to the renal arteries and then Na + , K + -ATPase activity was measured in the renal ...

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