全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Bruno Madio , Glenn F. King , Eivind A. B. Undheim
来源:[J].Marine Drugs(IF 3.978), 2019, Vol.17 (6)DOAJ
摘要:Sea anemones produce venoms of exceptional molecular diversity, with at least 17 different molecular scaffolds reported to date. These venom components have traditionally been classified according to pharmacological activity and amino acid sequence. However, this classification s...
作者:Volker Herzig , Glenn F. King
来源:[J].Toxins(IF 2.129), 2015, Vol.7 (10), pp.4366-4380DOAJ
摘要:The inhibitor cystine knot (ICK) is an unusual three-disulfide architecture in which one of the disulfide bonds bisects a loop formed by the two other disulfide bridges and the intervening sections of the protein backbone. Peptides containing an ICK motif are frequently cons...
作者:... Christiane Weirauch , Bryan G. Fry , Glenn F. King
来源:[J].Toxins(IF 2.129), 2016, Vol.8 (2)DOAJ
摘要:The piercing-sucking mouthparts of the true bugs (Insecta: Hemiptera: Heteroptera) have allowed diversification from a plant-feeding ancestor into a wide range of trophic strategies that include predation and blood-feeding. Crucial to the success of each of these strategies is th...
作者:Eivind A. B. Undheim , Bryan G. Fry , Glenn F. King
来源:[J].Toxins(IF 2.129), 2015, Vol.7 (3), pp.679-704DOAJ
摘要:Centipedes are among the oldest extant venomous predators on the planet. Armed with a pair of modified, venom-bearing limbs, they are an important group of predatory arthropods and are infamous for their ability to deliver painful stings. Despite this, very little is known about ...
作者:... Eivind A. B. Undheim , Glenn F. King , Lachlan D. Rash
来源:[J].Toxins(IF 2.129), 2015, Vol.7 (7), pp.2494-2513DOAJ
摘要:Voltage-gated sodium (NaV) channels are responsible for propagating action potentials in excitable cells. NaV1.7 plays a crucial role in the human pain signalling pathway and it is an important therapeutic target for treatment of chronic pain. Numerous spider venom peptides ...
作者:... Grant A. Ramm , John J. Miles , Glenn F. King
来源:[J].Scientific Reports(IF 2.927), 2018, Vol.8 (1), pp.1-14DOAJ
摘要:Abstract Consistent with their diverse pharmacology, peptides derived from venomous animals have been developed as drugs to treat disorders as diverse as hypertension, diabetes and chronic pain. Melanoma has a poor prognosis due in part to its metastatic capacity, warranting furt...
作者:... Volker Herzig , Lachlan D. Rash , Glenn F. King
来源:[J].Toxins(IF 2.129), 2010, Vol.2 (12), pp.2851DOAJ
摘要:Spiders are the most successful venomous animals and the most abundant terrestrial predators. Their remarkable success is due in large part to their ingenious exploitation of silk and the evolution of pharmacologically complex venoms that ensure rapid subjugation of prey. Most sp...
作者:Glenn F. King , Syed A. Ali ...
来源:[J].Toxins(IF 2.129), 2013, Vol.5 (12), pp.2488-2503DOAJ
摘要:Although known for their potent venom and ability to prey upon both invertebrate and vertebrate species, the Barychelidae spider family has been entirely neglected by toxinologists. In striking contrast, the sister family Theraphosidae (commonly known as tarantulas), which last s...
作者:... Gerardo Corzo , Bryan G. Fry , Glenn F. King
来源:[J].Cellular and Molecular Life Sciences(IF 5.615), 2018, Vol.75 (17), pp.3215-3229Springer
摘要:Abstract(#br)True Bugs (Insecta: Heteroptera) produce venom or saliva with diverse bioactivities depending on their feeding strategies. However, little is known about the molecular evolution of the venom toxins underlying these biological activities. We examined venom of the gian...

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