全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Georgios N. Tsaousis , Eirini Papadopoulou ...
来源:[J].Cancer Genetics(IF 1.915), 2018, Vol.220, pp.1-12Elsevier
摘要:Germline mutations in the BRCA1 and BRCA2 genes are associated with hereditary predisposition to breast and ovarian cancer. Sensitive and accurate detection of BRCA1 and BRCA2 mutations is crucial for personalized clinical management of individuals affected by breast or ovarian c...
作者:Georgios N. Tsaousis , Pantelis G. Bagos , Stavros J. Hamodrakas
来源:[J].BBA - Proteins and Proteomics(IF 3.733), 2014, Vol.1844 (2), pp.316-322Elsevier
摘要:Abstract(#br)During the last two decades a large number of computational methods have been developed for predicting transmembrane protein topology. Current predictors rely on topogenic signals in the protein sequence, such as the distribution of positively charged residues in ext...
作者:Georgios N. Tsaousis , Nikos C. Papandreou
来源:[J].BBA - Proteins and Proteomics(IF 3.733), 2016, Vol.1864 (7), pp.747-754Elsevier
摘要:Abstract(#br)A large number of modular domains that exhibit specific lipid binding properties are present in many membrane proteins involved in trafficking and signal transduction. These domains are present in either eukaryotic peripheral membrane or transmembrane proteins and ar...
作者:Ioly Kotta-Loizou , Georgios N. Tsaousis , Stavros J. Hamodrakas
来源:[J].BBA - Proteins and Proteomics(IF 3.733), 2013, Vol.1834 (4), pp.798-807Elsevier
摘要:Abstract(#br)Molecular Recognition Features (MoRFs) are defined as short, intrinsically disordered regions in proteins that undergo disorder-to-order transition upon binding to their partners. As their name suggests, they are implicated in molecular recognition, which serves...
作者:Georgios N. Tsaousis , Kimon E. Kremizas ...
来源:[J].BioMed Research International, 2014, Vol.2014Hindawi
摘要:A major part of membrane function is conducted by proteins, both integral and peripheral. Peripheral membrane proteins temporarily adhere to biological membranes, either to the lipid bilayer or to integral membrane proteins with noncovalent interactions. The aim of this study was...
作者:Pantelis G. Bagos , Georgios N. Tsaousis , Stavros J. Hamodrakas
来源:[J].Genomics, Proteomics & Bioinformatics, 2009, Vol.7 (3), pp.128-137Elsevier
摘要:It has been shown that the progress in the determination of membrane protein structure grows exponentially, with approximately the same growth rate as that of the water-soluble proteins. In order to investigate the effect of this, on the performance of prediction algorithms ...
作者:Georgios N. Tsaousis , Konstantinos D. Tsirigos ...
来源:[J].Bioinformatics(IF 5.323), 2010, Vol.26 (19), pp.2490-2492Oxford U Press
摘要:Summary: ExTopoDB is a publicly accessible database of experimentally derived topological models of transmembrane proteins. It contains information collected from studies in the literature that report the use of biochemical methods for the determination of the topology of α...
作者:Foivos Gypas , Georgios N. Tsaousis , Stavros J. Hamodrakas
来源:[J].Bioinformatics(IF 5.323), 2013, Vol.29 (19), pp.2517-2518Oxford U Press
摘要:Summary: Molecular recognition features (MoRFs) are small, intrinsically disordered regions in proteins that undergo a disorder-to-order transition on binding to their partners. MoRFs are involved in protein–protein interactions and may function as the initial step in molec...

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