全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Shaney L. Barratt , Gavin I. Welsh , Ann B. Millar
来源:[J].Respiratory Research(IF 3.642), 2017, Vol.18 (1)Springer
摘要:Alternative splicing of Vascular endothelial growth factor-A mRNA transcripts (commonly referred as VEGF) leads to the generation of functionally differing isoforms, the relative amounts of which have potentially significant physiological outcomes in conditions such as acute resp...
作者:... Rachel Lennon , Gavin I. Welsh , Richard J. M. Coward
来源:[J].Diabetologia(IF 6.487), 2017, Vol.60 (11), pp.2299-2311Springer
摘要:Podocytes are insulin - responsive cells of the glomerular filtration barrier and are key in preventing albuminuria, a hallmark feature of diabetic nephropathy. While there is evidence that a loss of insulin signalling to podocytes is detrimental, the molecular mechanisms underpi...
作者:... Aleksandr I. Evstifeev , Gavin I. Welsh , Nikolay V. Kotov
来源:[J].BMC Systems Biology(IF 2.982), 2016, Vol.10 (1)Springer
摘要:Abstract(#br) Background(#br)Second messengers, such as calcium, regulate the activity of multisite binding proteins in a concentration-dependent manner. For example, calcium binding has been shown to induce conformational transitions in the calcium-dependent protein calmodulin, ...
作者:Katherine A. Birchenall , Gavin I. Welsh , Andrés López Bernal
来源:[J].International Journal of Environmental Research and Public Health(IF 1.998), 2019, Vol.16 (9)DOAJ
摘要:The mechanism of human labour remains poorly understood, limiting our ability to manage complications of parturition such as preterm labour and induction of labour. In this study we have investigated the effect of labour on plasma metabolites immediately following delivery, ...
作者:Gavin I. Welsh , Moin A. Saleem
来源:[J].Acta Biomaterialia(IF 5.093), 2018, Vol.78, pp.111-122Elsevier
摘要:Abstract(#br)Recreating tissue-specific microenvironments of the extracellular matrix (ECM) in vitro is of broad interest for the fields of tissue engineering and organ-on-a-chip. Here, we present biofunctional ECM protein fibres and suspended membranes, with tuneable bioche...
作者:Gavin I. Welsh , Agnieszka Bierzynska ...
来源:[J].The American Journal of Human Genetics(IF 11.202), 2019, Vol.104 (2), pp.348-355Elsevier
摘要:Steroid-resistant nephrotic syndrome (SRNS) is characterized by high-range proteinuria and most often focal and segmental glomerulosclerosis (FSGS). Identification of mutations in genes causing SRNS has improved our understanding of disease mechanisms and highlighted defects...
作者:Gavin I. Welsh , C. Charles Michel ...
来源:[J].Kidney International(IF 7.916), 2018, Vol.93 (5), pp.1086-1097Elsevier
摘要:Increased urinary albumin excretion is a key feature of glomerular disease but has limitations as a measure of glomerular permeability. Here we describe a novel assay to measure the apparent albumin permeability of single capillaries in glomeruli, isolated from perfused kidneys c...

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