全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... C. E Umebese , O Abiodun , G. O. Gbotosho
来源:[J].Parasitology Research(IF 2.852), 2016, Vol.115 (1), pp.299-305Springer
摘要:Abstract(#br)The use of plant to meet health-care needs has greatly increased worldwide in the recent times. The search for new plant-derived bioactive agents that can be explored for the treatment of drug-resistant malaria infection is urgently needed. Thus, we evaluated th...
作者:G. O. Gbotosho , C. O. Falade ...
来源:[J].Tropical Medicine & International Health(IF 2.938), 2004, Vol.9 (5), pp.606-614Wiley
摘要:Summary(#br)Background Increasing drug resistance in Plasmodium falciparum has necessitated renewed search for cheap, effective alternatives to commonly available antimalarials, chloroquine and pyrimethamine–sulphadoxine, for the treatment of malaria in Africa. Probenecid, a...
作者:G. O. Gbotosho , E. Tambo ...
来源:[J].Tropical Medicine & International Health(IF 2.938), 2005, Vol.10 (11), pp.1161-1170Wiley
摘要:Summary(#br)Background Artemisinin‐based combination antimalarials are currently considered effective alternatives for the treatment of malaria in Africa, but there are few studies of such combinations in Nigerian children. We assessed the safety, treatment efficacy and effe...
作者:G. O. Gbotosho , A. A. Adedeji ...
来源:[J].Parasitology Research(IF 2.852), 2007, Vol.100 (3), pp.511-517Springer
摘要:Abstract(#br)An open randomized controlled study of artemether–lumefantrine (AL) and amodiaquine–sulfalene–pyrimethamine (ASP) for the treatment of uncomplicated Plasmodium falciparum malaria was carried out in 181 children. In 79 children, the hepatomegaly reduction ra...
作者:G. O. Gbotosho , O. A. Folarin ...
来源:[J].Parasitology Research(IF 2.852), 2006, Vol.100 (1), pp.141-148Springer
摘要:Abstract(#br)Chloroquine (CQ) resistance in Plasmodium falciparum is associated with polymorphisms in loci on pfcrt and pfmdr1 genes. In this study, we determined the association and linkage disequilibrium between in vivo CQ resistance and P. falciparum polymorphisms in pfcr...
作者:... C. T. HAPPI , A. SOWUNMI , G. O. GBOTOSHO
来源:[J].Parasitology(IF 2.355), 2015, Vol.142 (6), pp.849-854Cambridge U Press
摘要:SUMMARY Emergence of malaria parasites resistant to artemisinin necessitates the need for development of new antimalarial therapies. Ciprofloxacin (CFX) a second generation quinolone antibiotic possesses some antimalarial activities. We investigated the in vivo antimalarial ...
作者:G. O. Gbotosho , E. O. Ajaiyeoba ...
来源:[J].Journal of Parasitology Research, 2014, Vol.2014Hindawi
摘要:Drug resistance in Plasmodium falciparum requires that new drugs must be developed. Plants are a potential source for drug discovery and development. Two plants that used to treat febrile illnesses in Nigeria were tested for in vitro and in vivo antimalarial activity and cyt...

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