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作者:... J A Verhaar , M R Bernsen , G M van Buul
来源:[J].Eur Cell Mater(IF 4.558), 2018, Vol.36, pp.218-230European Cells and Materials (eCM)
摘要:Mesenchymal stem cells (MSCs) represent a promising biological therapeutic option as an osteoarthritis (OA)-modifying treatment. MSCs secrete factors that can counteract inflammatory and catabolic processes and attract endogenous repair cells. The effects of intra-articular ...
作者:... M R Bernsen , G M van Buul , G J van Osch
来源:[J].Eur Cell Mater(IF 4.558), 2017, Vol.33, pp.43-58European Cells and Materials (eCM)
摘要:Bone marrow derived mesenchymal stem cells (MSCs) have immunomodulatory and trophic capacities. For therapeutic application in local chronic inflammatory diseases, MSCs, preferably of allogeneic origin, have to retain immunomodulatory properties. This might be achieved by encapsu...

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