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作者:Frederick J. Kaskel , Milena K. Radeva ...
来源:[J].Kidney International(IF 7.916), 2011, Vol.79 (6), pp.678-685
摘要:Optimal therapy of patients with steroid-resistant primary focal segmental glomerulosclerosis (FSGS) remains controversial. This report describes the initial study design, baseline characteristics, and quality of life of patients enrolled in the FSGS Clinical Trial, a large ...
作者:Jerome C. Lane , Frederick J. Kaskel
来源:[J].Seminars in Nephrology(IF 2.828), 2009, Vol.29 (4), pp.389-398
摘要:Summary(#br)Remarkable advances have been made in the past decade in understanding the pathophysiology of idiopathic nephrotic syndrome. Although the initiating events leading to the onset of proteinuria still are not well defined, it has become increasingly clear that many glome...
作者:... Wayne Waltzer , Frederick J. Kaskel , Leonard Arbeit
来源:[J].American Journal of Kidney Diseases(IF 5.294), 1995, Vol.25 (1), pp.75-78
摘要:Abstract(#br)Cases of immunoglobulin A heavy chain and kappa light chain deposition disease are rare and their clinical presentations vary. We report one patient with histopathologic and clinical findings of a microangiopathic glomerulonephritis due to immunoglobulin A-κ dep...
作者:Frederick J. Kaskel , Robert A. Weiss
来源:[J].The Journal of Urology(IF 3.696), 2008, Vol.180 (4), pp.1700-1704
摘要:Purpose(#br)Little is known about health related quality of life in adolescents with chronic kidney disease due to urological anomalies. We assessed generic health related quality of life in this population using a validated parent proxy instrument.(#br)Materials and Methods...
作者:... Arlene C. Gerson , Frederick J. Kaskel , Susan L. Furth
来源:[J].The Journal of Urology(IF 3.696), 2007, Vol.178 (2), pp.660-665
摘要:Purpose(#br)We examined health related quality of life in adolescents with congenital urological disease causing kidney disease using a generic health related quality of life instrument. We then compared the results to those in adolescents with medical kidney disease and to popul...
作者:... Daniel Casellas , Frederick J. Kaskel , Leon C. Moore
来源:[J].Kidney International(IF 7.916), 1998, Vol.54, pp.S195-S198
摘要:Insulin-like growth factor-I restores microvascular autoregulation in experimental chronic renal failure. Impairment of autoregulation (AR) is associated with accelerated progression of chronic renal failure (CRF). As the bioavailability of insulin-like growth factor-I (IGF-...
作者:Frederick J. Kaskel , Charlotte M. Druschel
来源:[J].The Journal of Pediatrics(IF 4.035), 2008, Vol.154 (2), pp.263-266
摘要:Objective(#br)We investigated the prevalence of congenital renal and urologic anomalies in children with congenital hypothyroidism to determine whether further renal and urologic investigations would be of benefit.(#br)Study design(#br)Prevalence of congenital hypothyroidism was ...
作者:Frederick J. Kaskel , Jeffrey B. Kopp ...
来源:[J].The American Journal of Human Genetics(IF 11.202), 2018, Vol.103 (3), pp.367-376
摘要:Black Americans are at increased risk for preeclampsia. Genetic variants in apolipoprotein L1 ( APOL1 ) account for much of the increased risk for kidney disease in blacks. APOL1 is expressed in human placenta and transgenic mice expressing APOL1 develop preeclampsia. We evaluate...
作者:Saritha Ranabothu , Frederick J. Kaskel
来源:[J].Pediatric Nephrology(IF 2.939), 2015, Vol.30 (7), pp.1051-1052
摘要:Abstract(#br)Growth failure is a common problem in children with chronic kidney disease (CKD). The causes are multifactorial and are associated with increased mortality and morbidity. Standard deviations of bone age versus chronological age in children with CKD have not been deve...

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