全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Franz Marxreiter , Juergen Winkler ...
来源:[J].BMC Neurology(IF 2.564), 2017, Vol.17 (1)Springer
摘要:The loss of the swallow-tail sign of the substantia nigra has been proposed for diagnosis of Parkinson’s disease. Aim was to evaluate, if the sign occurs consistently in healthy subjects and if it can be reliably detected with high-resolution 7T susceptibility weighted imagi...
作者:Franz Marxreiter , Jochen Klucken
来源:[J].Sensors(IF 1.953), 2019, Vol.19 (14)DOAJ
摘要:Mobile gait analysis systems using wearable sensors have the potential to analyze and monitor pathological gait in a finer scale than ever before. A closer look at gait in Parkinson’s disease (PD) reveals that turning has its own characteristics and requires its own analysis...
作者:Franz Marxreiter , Zacharias Kohl ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (2)DOAJ
摘要:Motor impairments are the prerequisite for the diagnosis in Parkinson's disease (PD). The cardinal symptoms (bradykinesia, rigor, tremor, and postural instability) are used for disease staging and assessment of progression. They serve as primary outcome measures for clinical stud...
作者:Franz Marxreiter , Martin Regensburger , Jürgen Winkler
来源:[J].Cellular and Molecular Life Sciences(IF 5.615), 2013, Vol.70 (3), pp.459-473Springer
摘要:Abstract(#br)Parkinson’s disease (PD), the second most common neurodegenerative disorder, affects 1–2 % of humans aged 60 years and older. The diagnosis of PD is based on motor symptoms such as bradykinesia, rigidity, tremor, and postural instability associated with the stri...
作者:Franz Marxreiter , Benjamin Ettle ...
来源:[J].Neurobiology of Disease(IF 5.624), 2013, Vol.59, pp.38-51Elsevier
摘要:Abstract(#br)In Parkinson's disease (PD) patients, alpha-synuclein (α-syn) pathology advances in form of Lewy bodies and Lewy neurites throughout the brain. Clinically, PD is defined by motor symptoms that are predominantly attributed to the dopaminergic cell loss in the sub...
作者:Franz Marxreiter , Brit Mollenhauer ...
来源:[J].Autophagy(IF 12.042), 2018, Vol.14 (1), pp.98-119Taylor & Francis
摘要:ABSTRACT(#br)The autophagy-lysosome pathway (ALP) regulates intracellular homeostasis of the cytosolic protein SNCA/alpha-synuclein and is impaired in synucleinopathies, including Parkinson disease and dementia with Lewy bodies (DLB). Emerging evidence suggests that ALP infl...
作者:Franz Marxreiter , Simon Steib ...
来源:[J].Frontiers in Neurology, 2017, Vol.8DOAJ
摘要:IntroductionCognitive and gait deficits are common symptoms in Parkinson’s disease (PD). Motor-cognitive dual tasks (DTs) are used to explore the interplay between gait and cognition. However, it is unclear if DT gait performance is indicative for cognitive impairment. There...
作者:Franz Marxreiter , Martin Regensburger ...
来源:[J].Restorative Neurology and Neuroscience(IF 2.929), 2014, Vol.32 (4), pp.447-462IOS Press
摘要:Purpose: Parkinson's disease (PD) is characterized by striatal synaptic deafferentation followed by dopaminergic cell death in the substantia nigra pars compacta. Not only degenerative, but also regenerative, compensatory changes at distant sites of the primary lesion may oc...
作者:Franz Marxreiter , Julia Gossler ...
来源:[J].PLOS ONE(IF 3.73), 2017, Vol.12 (10)PLOS
摘要:Distinct gait characteristics like short steps and shuffling gait are prototypical signs commonly observed in Parkinson’s disease. Routinely assessed by observation through clinicians, gait is rated as part of categorical clinical scores. There is an increasing need to provi...

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