全部文献期刊会议图书|学者科研项目
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作者:Frans K. Gorus , Åke Lernmark ...
来源:[J].Journal of Immunological Methods(IF 2.225), 2007, Vol.319 (1), pp.133-143
摘要:Abstract(#br)The 65 kDa isoform of human glutamate decarboxylase (GAD65) is a major autoantigen in type 1 diabetes (T1D). In the present study, we have developed a sensitive sandwich time-resolved fluorescence immunoassay (TRFIA) for the quantification of GAD65 in cell extracts, ...
作者:Frans K. Gorus , Ilse Weets ...
来源:[J].Diabetes Research and Clinical Practice(IF 2.741), 2014, Vol.103 (1), pp.97-105
摘要:Abstract(#br)Aims(#br)We investigated the prevalence of diabetes autoantibodies (Abs) in Cameroonian patients and controls, assessed their contribution in disease classification and compared results with data from Belgium.(#br)Methods(#br)Abs against GAD (GADA), IA-2 (IA-2A)...
作者:... Chris Van Schravendijk , Frans K. Gorus , Bart J.R. Van der Auwera
来源:[J].Human Immunology(IF 2.298), 2010, Vol.71 (12), pp.1233-1237
摘要:Abstract(#br)Our goals were to study the proposed association of IL-2RA /CD25 with type 1 diabetes in the Belgian population over a broad age range, and to explore possible correlations with disease phenotypes, immune markers, HLA-DQ , INS , and PTPN22 . Patients ( n = 1954)...
作者:... Françoise Vertongen , Frans K. Gorus , Bart J. Van der Auwera
来源:[J].Human Immunology(IF 2.298), 2004, Vol.65 (7), pp.729-736
摘要:Abstract(#br)The heterozygous combination of DQA1*03-DQB1*0302 (DQ8) and DQA1*05-DQB1*0201 (DQ2) confers the highest known HLA-DQ-linked risk for type 1 diabetes, suggesting a role for transcomplementation. The trans -heterodimer encoded by DQA1*03 and DQB1*02 is also rarely...
作者:... Chris Van Schravendijk , Frans K. Gorus , Bart J.R. Van der Auwera
来源:[J].Human Immunology(IF 2.298), 2007, Vol.68 (8), pp.690-697
摘要:Summary(#br)To determine the contribution of the tumor necrosis factorα gene (TNFA) to the immunogenetic risk prediction of type 1 diabetes (T1D) in the Belgian population, well-characterized antibody-positive patients with type 1 diabetes (T1D), nondiabetic control subjects...
作者:Daniele E. Hasaerts , Frans K. Gorus , Linda J. De Meirleir
来源:[J].Pediatric Neurology(IF 1.416), 1998, Vol.18 (5), pp.432-434
摘要:Abstract(#br)An 11-month-old boy with a relapsing dancing eye syndrome associated with elevation of serum alkaline phosphatase, lactate dehydrogenase, and aminotransferase activities is reported. During two clinical episodes the serum alkaline phosphatase activity increased up to...

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