全部文献期刊会议图书|学者科研项目
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作者:Frank Jacobsen , Juliane Kraft ...
来源:[J].Neoplasia, 2017, Vol.19 (9), pp.707-715
摘要:Abstract(#br)Biglycan (BGN), a proteoglycan of the extracellular matrix, is included in mRNA signatures for prostate cancer aggressiveness. To understand the impact of BGN on prognosis and its relationship to molecularly defined subsets, we analyzed BGN expression by immunohistoc...
作者:... Till Clauditz , Sarah Minner , Frank Jacobsen
来源:[J].Human Pathology(IF 2.843), 2017, Vol.61, pp.210-220
摘要:Summary(#br)Development of genetic instability is a hallmark of tumor progression. Type III β -tubulin (TUBB3) is a component of microtubules involved in chromosome segregation. Its overexpression has been linked to adverse features of urinary bladder cancer. To investigate ...
作者:Frank Jacobsen , Dirk Hoefer
来源:[J].Journal of Plastic, Reconstructive & Aesthetic Surgery(IF 1.439), 2018, Vol.71 (1), pp.101-111
摘要:Summary(#br)Background(#br)Adipose-derived stem cells represent an interesting option for soft tissue replacement as they are easy to procure and can generate their own blood supply through the production of angiogenic factors. We seeded adipose-derived stem cells on a bioresorba...
作者:Frank Jacobsen , Sarah Minner ...
来源:[J].Neoplasia, 2017, Vol.19 (4), pp.279-287
摘要:Abstract(#br)The A Disintegrin and Metalloproteinase (ADAM) family of endopeptidases plays a role in many solid cancers and includes promising targets for anticancer therapies. Deregulation of ADAM15 has been linked to tumor aggressiveness and cell line studies suggest that ADAM1...
作者:Frank Jacobsen , Andrea Rittig ...
来源:[J].Experimental Cell Research(IF 3.557), 2013, Vol.319 (12), pp.1724-1731
摘要:Abstract(#br)Soft tissue sarcomas (STS) are characterized by co-participation of several epigenetic and genetic events during tumorigenesis. Having bypassed cellular senescence barriers during oncogenic transformation, the factors further affecting growth rate of STS cells r...
作者:Frank Jacobsen , Joachim Dissemond ...
来源:[J].Journal of Surgical Research(IF 2.018), 2009, Vol.164 (2), pp.344-350
摘要:Background(#br)Skin antiseptics are widely used in health-care worldwide. However, there is a need to determine cytotoxicity of these medications on wounds. The aim of this study was to evaluate cytotoxic effects of five clinically used antiseptics on human skin cells.(#br)Materi...
作者:... Ursula Kraneburg , Frank Jacobsen , Sammy Al-Benna
来源:[J].Immunobiology(IF 2.814), 2010, Vol.216 (3), pp.322-333
摘要:Abstract(#br)Host defence peptides (HDPs) are short cationic molecules produced by the immune systems of most multicellular organisms and play a central role as effector molecules of innate immunity. Host defence peptides have a wide range of biological activities from direct kil...
作者:Frank Jacobsen , Kilian Kreutzer ...
来源:[J].British Journal of Oral & Maxillofacial Surgery(IF 2.717), 2009, Vol.48 (2), pp.131-135
摘要:Abstract(#br)We evaluated the use of multilayer human amniotic membrane (HAM) as a grafting material for the repair of mid-palate oronasal fistulas in seven Berlin minipigs. After two weeks, three animals had the fistulas repaired with multilayered HAM grafts, three had them...
作者:Frank Jacobsen , Lars Steinsträßer ...
来源:[J].Journal of Investigative Dermatology(IF 6.193), 2014, Vol.134 (11), pp.2823-2832
摘要:As the outermost barrier of the body, the skin is exposed to multiple environmental factors, including temperature, humidity, mechanical stress, and chemical stimuli such as odorants that are often used in cosmetic articles. Keratinocytes, the major cell type of the epiderma...
作者:Frank Jacobsen , Tim Luetkens ...
来源:[J].Experimental and Molecular Pathology(IF 2.128), 2010, Vol.89 (2), pp.175-181
摘要:Abstract(#br)Cancer-testis (CT) antigens are promising targets for antigen-specific therapy of multiple myeloma (MM). Osteolytic lesions represent the most common clinical manifestation of myeloma and it is possible that osseous myeloma lesions differ from bone-infiltrating ...

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