全部文献期刊会议图书|学者科研项目
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作者:... Martina C. Herwig-Carl , Frank G. Holz , Karin U. Loeffler
来源:[J].Graefe's Archive for Clinical and Experimental Ophthalmology(IF 1.932), 2017, Vol.255 (11), pp.2277-2285
摘要:The purpose of the study was to evaluate the characteristics of sebaceous gland carcinoma (SGC) of the ocular adnexae, which is due to a high variability in clinical, histological and immunohistochemical characteristics often challenging to diagnose.
作者:Frank G. Holz , Giovanni Staurenghi ...
来源:[J].Ophthalmology(IF 5.563), 2020, Vol.127 (3), pp.394-409
摘要:Purpose(#br)To describe the defining features of incomplete retinal pigment epithelium (RPE) and outer retinal atrophy (iRORA), a consensus term referring to the OCT-based anatomic changes often identified before the development of complete RPE and outer retinal atrophy (cRORA) i...
作者:... James Warburton , Andreas Weichselberger , Frank G. Holz
来源:[J].Ophthalmology(IF 5.563), 2020, Vol.127 (1), pp.72-84
摘要:Purpose(#br)Two similarly designed phase 3 trials (HAWK and HARRIER) compared brolucizumab, a single-chain antibody fragment that inhibits vascular endothelial growth factor-A, with aflibercept to treat neovascular age-related macular degeneration (nAMD).(#br)Design(#br)Doub...
作者:Frank G. Holz , Anna Melissa Schlitter
来源:[J].Experimental Eye Research(IF 3.026), 2019, Vol.182, pp.175-181
摘要:Abstract(#br)Cancer evolves from a combination of genetic and epigenetic abnormalities resulting in aberrant gene expression profiles as well as altered epigenomic patterns. Epigenetic alterations such as DNA methylation and histone modification play an important role in tum...
作者:Frank G. Holz , Robert E. MacLaren
来源:[J].American Journal of Ophthalmology(IF 3.631), 2019, Vol.199, pp.19-27
摘要:Purpose(#br)To investigate near-infrared fundus autofluorescence (NIR-AF) characteristics in patients with choroideremia and to correlate these with anatomic and functional parameters.(#br)Design(#br)Retrospective, observational case series.(#br)Methods(#br)In this multicent...
作者:Frank G. Holz , Jeffrey S. Heier ...
来源:[J].Ophthalmology(IF 5.563), 2018
摘要:Purpose(#br)To determine whether emixustat hydrochloride (emixustat) reduces the rate of enlargement of geographic atrophy (GA) compared with placebo in subjects with age-related macular degeneration (AMD) and to evaluate the safety and tolerability of emixustat over 24 mont...
作者:Frank G. Holz , Adrian Koh ...
来源:[J].Ophthalmology(IF 5.563), 2019
摘要:Improving or maintaining visual acuity is the main goal for the treatment of neovascular age-related macular degeneration (nAMD). Current nAMD standard of care dictates frequent intravitreal (IVT) anti–vascular endothelial growth factor (VEGF) injections, which places a subs...
作者:Frank G. Holz , Christopher Brittain ...
来源:[J].Ophthalmology(IF 5.563), 2018, Vol.125 (3), pp.369-390
摘要:Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) that leads to progressive and irreversible loss of visual function. Geographic atrophy is defined by the presence of sharply demarcated atrophic lesions of the outer retina, resulting from ...
作者:... Sarah Thiele , Frank G. Holz , Philipp Herrmann
来源:[J].American Journal of Ophthalmology(IF 3.631), 2018
摘要:Purpose(#br)To evaluate macular pigment distribution pattern as a prognostic marker for disease progression in patients with macular telangiectasia type 2 (MacTel).(#br)Design(#br)Retrospective cohort study(#br)Methods(#br)In this single-center study, 90 eyes of 47 patients ...
作者:Frank G. Holz , Steffen Schmitz-Valckenberg ...
来源:[J].Ophthalmology(IF 5.563), 2018, Vol.125 (4), pp.537-548
摘要:Purpose(#br)To develop consensus terminology and criteria for defining atrophy based on OCT findings in the setting of age-related macular degeneration (AMD).(#br)Design(#br)Consensus meeting.(#br)Participants(#br)Panel of retina specialists, image reading center experts, re...

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