全部文献期刊会议图书|学者科研项目
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作者:Frank Bepperling , Manfred Wargenau
来源:[J].Journal of Anesthesia(IF 0.867), 2012, Vol.26 (6), pp.851-857Springer
摘要:Abstract(#br) Purpose(#br)This phase I study was performed in volunteers of Japanese ethnicity to compare pharmacokinetic data after infusion of 6 % hydroxyethyl starch (HES) 130/0.4 with historical data of Caucasians.(#br) Methods(#br)In an open-label, uncontrolled, single-...
作者:... Manfred Wargenau , Frank Bepperling , Jean-François Baron
来源:[J].Anesthesia & Analgesia(IF 3.3), 2002, Vol.95 (3), pp.544-551Wolters Kluwer
摘要:Hydroxyethyl starches (HES) are almost exclusively excreted glomerularly, in part after hydrolysis by amylase. HES 130/0.4 (Voluven; Fresenius Kabi Deutschland GmbH, Bad Homburg, Germany) was developed to improve pharmacokinetics whereas preserving the efficacy of volume eff...
作者:... Daniela Baus , Frank Bepperling , David C. Warltier
来源:[J].Anesthesiology(IF 5.163), 2007, Vol.106 (6), pp.1120-1127Wolters Kluwer
摘要:BACKGROUND:: The purpose of this study was to test the equivalence of efficacy and compare the safety of the 6% hydroxyethyl starches (HES) Voluven® (HES 130/0.4; Fresenius Kabi, Bad Homburg, Germany) and hetastarch (HES 670/0.75 in saline) for intravascular volume replaceme...
作者:Frank Bepperling , Hideki Miyao ...
来源:[J].Open Journal of Anesthesiology, 2013, Vol.3 (7), pp.326-337Scientific Research Publishing
摘要:Purpose: Theprimary aim of this study was to investigate volume effect and safety of up to50 mL/kg BW 6% hy droxyethyl starch (HES) 130/0.4 in adult and pediatric patientsundergoing major elective surgery. The need to infuse human albumin may bereduced or avoided in Japan if thes...
作者:Frank Bepperling , Hideki Miyao ...
来源:[J].Open Journal of Anesthesiology, 2013, Vol.3 (7), pp.326-337Airiti
摘要:Purpose: The primary aim of this study was to investigate volume effect and safety of up to 50 mL/kg BW 6% hydroxyethyl starch (HES) 130/0.4 in adult and pediatric patients undergoing major elective surgery. The need to infuse human albumin may be reduced or avoided in Japan...

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