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作者:Fernando Huete-Toral , Alejandro Martínez-Águila ...
来源:[J].Pharmacogenetics and Genomics(IF 3.608), 2011, Vol.21 (9), pp.587-589
摘要:We have demonstrated that 5-methoxycarbonylamino-N-acetyltryptamine (5-MCA-NAT), reduces intraocular pressure (IOP) in rabbits. In addition, we have reported a link between hypotensive effect of 5-MCA-NAT and sympathetic nervous system. Moreover, it is known that aqueous humour p...
作者:Fernando Huete-Toral , Alejandro Martí ...
来源:[J].Expert Opinion on Drug Discovery(IF 2.297), 2012, Vol.7 (10), pp.989-1001
摘要:Introduction:   The pineal indole-derived hormone melatonin is a modulator of circadian and seasonal rhythms with an important role in ocular health and disease. This could be due to specific melatonin receptors that have been identified in structures such as cornea, lens,...
作者:... Almudena Crooke , Fernando Huete-Toral , Jesus Pintor
来源:[J].Expert Opinion on Pharmacotherapy(IF 2.86), 2014, Vol.15 (10), pp.1371-1390
摘要:Introduction: Dry eye disease is a common disorder provoking changes in tear film and ocular surface. Untreated dry eye could cause ocular infections, corneal ulcer and blindness. Only a few drugs are authorized so far for the treatment of dry eye disease and the possibilities of...

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