全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Federica Capozzi , Lorenzo D’Ambrosio ...
来源:[J].Molecular Cancer(IF 5.134), 2017, Vol.16 (1)Springer
摘要:Enhancing the antitumor activity of the DNA-damaging drugs is an attractive strategy to improve current treatment options. Trabectedin is an isoquinoline alkylating agent with a peculiar mechanism of action. It binds to minor groove of DNA inducing single- and double-strand-break...
作者:Federica Capozzi , Marta Canta ...
来源:[J].BMC Cancer(IF 3.333), 2015, Vol.15 (1)Springer
摘要:Abstract(#br) Background(#br)Malignant Pleural Mesothelioma (MPM) is an aggressive tumor arising from mesothelial cells lining the pleural cavities characterized by resistance to standard therapies. Most of the molecular steps responsible for pleural transformation remain un...
作者:Federica Capozzi , Roberto Biagini ...
来源:[J].Lancet Oncology(IF 25.117), 2015, Vol.16 (1), pp.98-107Elsevier
摘要:Summary(#br)Background(#br)Results of previous study showed promising but short-lived activity of sorafenib in the treatment of patients with unresectable advanced and metastatic osteosarcoma. This treatment failure has been attributed to the mTOR pathway and might therefore...

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