全部文献期刊会议图书|学者科研项目
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作者:Esther Nkuipou-Kenfack , Agnieszka Latosinska ...
来源:[J].Critical Care, 2020, Vol.24 (29), pp.849-856
摘要:Abstract(#br)Rationale(#br)The urinary proteome reflects molecular drivers of disease. Objectives(#br)To construct a urinary proteomic biomarker predicting 1-year post-ICU mortality. Methods(#br)In 1243 patients, the urinary proteome was measured on ICU admission, using capi...
作者:Esther Nkuipou-Kenfack , Wen-Yi Yang ...
来源:[J].Journal of the American Society of Hypertension(IF 2.835), 2018, Vol.12 (6), pp.438-447.e4
摘要:Abstract(#br)Hypertension, obesity, and old age are major risk factors for left ventricular (LV) diastolic dysfunction (LVDD), but easily applicable screening tools for people at risk are lacking. We investigated whether HF1, a urinary biomarker consisting of 85 peptides, ca...
作者:Esther Nkuipou-Kenfack , Flore Duranton ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.9 (5)
摘要:Chronic kidney disease (CKD) is part of a number of systemic and renal diseases and may reach epidemic proportions over the next decade. Efforts have been made to improve diagnosis and management of CKD. We hypothesised that combining metabolomic and proteomic approaches cou...
作者:Esther Nkuipou-Kenfack , Joost P Schanstra ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.12 (2)
摘要:Ageing is a complex process characterised by a systemic and progressive deterioration of biological functions. As ageing is associated with an increased prevalence of age-related chronic disorders, understanding its underlying molecular mechanisms can pave the way for therapeutic...
作者:Esther Nkuipou-Kenfack , Harald Mischak ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.11 (6)
摘要:Biomarker discovery and new insights into the pathophysiology of heart failure with reduced ejection fraction (HFrEF) may emerge from recent advances in high-throughput urinary proteomics. This could lead to improved diagnosis, risk stratification and management of HFrEF.Urine sa...
作者:Esther Nkuipou-Kenfack , Adela Ramirez-Torres ...
来源:[J].PLoS ONE(IF 3.73), 2018, Vol.12 (3)
摘要:Identification of individuals who are at risk of suffering from acute coronary syndromes (ACS) may allow to introduce preventative measures. We aimed to identify ACS-related urinary peptides, that combined as a pattern can be used as prognostic biomarker. Proteomic data of 2...
作者:Esther Nkuipou-Kenfack , Petra Zürbig ...
来源:[J].Scientific Reports(IF 2.927), 2019, Vol.9 (1), pp.1-12
摘要:Abstract Kidney function is altered by age together with a declined filtration capacity of 5–10% per decade after 35 years. Renal aging shares many characteristics with chronic kidney disease. Plasma levels of the bioactive peptide apelin also decline with age and apelin has...
作者:Esther Nkuipou-Kenfack , Petra Zürbig ...
来源:[J].Scientific Reports(IF 2.927), 2019, Vol.9 (7), pp.569-579
摘要:Abstract(#br)Kidney function is altered by age together with a declined filtration capacity of 5–10% per decade after 35 years. Renal aging shares many characteristics with chronic kidney disease. Plasma levels of the bioactive peptide apelin also decline with age and apelin...
作者:Esther Nkuipou-Kenfack , William Spooner ...
来源:[J].BMC Bioinformatics(IF 3.024), 2016, Vol.17 (1)
摘要:Abstract(#br) Background(#br)When combined with a clinical outcome variable, the size, complexity and nature of mass-spectrometry proteomics data impose great statistical challenges in the discovery of potential disease-associated biomarkers. The purpose of this study was thus to...
作者:Esther Nkuipou-Kenfack , Holger Engel ...
来源:[J].Journal of Microbiological Methods(IF 2.161), 2013, Vol.93 (1), pp.20-24
摘要:Abstract(#br)Viability PCR (v-PCR) as a method to selectively detect intact live cells has gained considerable interest over the last years with an increasing number of applications. The principle is based on treatment of microbiological samples with a viability dye prior to...

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