全部文献期刊会议图书|学者科研项目
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作者:Ellen Obermann , Uwe Güth ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.7 (8)DOAJ
摘要:KCNMA1 encodes the α-subunit of the large conductance, voltage and Ca(2+)-activated (BK) potassium channel and has been reported as a target gene of genomic amplification at 10q22 in prostate cancer. To investigate the prevalence of the amplification in other human cancers, ...
作者:Ellen Obermann , Christian Ohlschlegel ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.7 (5)DOAJ
摘要:UNLABELLED: Adjuvant chemotherapy decisions in breast cancer are increasingly based on the pathologist's assessment of tumor proliferation. The Swiss Working Group of Gyneco- and Breast Pathologists has surveyed inter- and intraobserver consistency of Ki-67-based proliferative fr...
作者:... Michael Fiegl , Ellen Obermann , Alexandar Tzankov
来源:[J].Journal of Thoracic Oncology(IF 4.473), 2014, Vol.9 (1), pp.41-49Elsevier
摘要:Introduction:(#br)The cancer stem cell (CSC) theory postulates the existence of a distinct population of undifferentiated cells responsible for tumor initiation and maintenance. CSCs may be naturally resistant to the cytotoxic effect of radio-chemotherapy because of slow cel...
作者:Ellen Obermann , Gieri Cathomas
来源:[J].Human Pathology(IF 2.843), 2013, Vol.44 (12), pp.2727-2735Elsevier
摘要:Summary(#br)Prostate cancer is a heterogeneous, frequently multifocal disease with a broad spectrum of clinical, pathologic, and molecular characteristics. The TMPRSS2-ERG gene rearrangement is highly specific for prostate cancer. We used immunohistochemistry as a surrogate ...
作者:... Michelle Herzog , Ellen Obermann , Lukas Bubendorf
来源:[J].Journal of Thoracic Oncology(IF 4.473), 2013, Vol.8 (8), pp.1004-1011Elsevier
摘要:Introduction:(#br)Lung cancer is often diagnosed by cytology, necessitating predictive molecular marker analyses on cytological specimens. The gold standard for detection of predictive anaplastic lymphoma kinase (ALK)-rearrangements is fluorescence in situ hybridization (FIS...
作者:Ellen Obermann , Daniel Fink ...
来源:[J].The Journal of Pathology(IF 7.585), 2014, Vol.234 (2), pp.239-252Wiley
摘要:Abstract(#br)Endometrial cancer is the most frequently occurring malignancy of the female genital tract in Western countries. Although in many cases surgically curable, about 30% of the tumours represent an aggressive and untreatable disease. In an attempt to establish a rel...
作者:... Dorothy Jane Huang , Ellen Obermann , Hansjakob Müller
来源:[J].Familial Cancer(IF 1.935), 2011, Vol.10 (1), pp.73-77Springer
摘要:Abstract(#br)The term “familial male breast cancer” is often misleading, because in the breast cancer families reported in the literature, the vast majority of the patients were women and only a few were men. In this report, we present the rare case of a strictly defined fam...
作者:Ellen Obermann , Thomas Singer ...
来源:[J].PLOS ONE(IF 3.73), 2016, Vol.11 (8)PLOS
摘要:The use of patients’ own cancer cells for in vitro selection of the most promising treatment is an attractive concept in personalized medicine. Human carcinoma cells from malignant pleural effusions (MPEs) are suited for this purpose since they have already adapted to the li...
作者:Ellen Obermann , Christian Ohlschlegel ...
来源:[J].PLOS ONE(IF 3.73), 2012, Vol.7 (5)PLOS
摘要:Adjuvant chemotherapy decisions in breast cancer are increasingly based on the pathologist's assessment of tumor proliferation. The Swiss Working Group of Gyneco- and Breast Pathologists has surveyed inter- and intraobserver consistency of Ki-67-based proliferative fraction ...
作者:Ellen Obermann , Stefanie Meyer ...
来源:[J].Oncology Reports(IF 2.297), 2004, Vol.11 (4), pp.745-751Spandidos
摘要:Investigation of early urothelial lesions is essential to gain insightinto the development of bladder cancer. In order to evaluate if deletions of chromosomearms 9p and 9q are preceding histomorphological changes in the urothelium, histologicallynormal urothelial samples of patie...

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