全部文献期刊会议图书|学者科研项目
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作者:Eleonora Veglia , Monica Argenziano ...
来源:[J].Pharmacological Research(IF 4.346), 2018, Vol.128, pp.18-28
摘要:Abstract(#br)Due to the incidence of diabetes and the related morbidity of diabetic nephropathy, identification of new therapeutic strategies represents a priority. In the last few decades new and growing evidence on the possible role of histamine in diabetes has been provided. I...
作者:Eleonora Veglia , Alessandro Pini ...
来源:[J].Pharmacological Research(IF 4.346), 2016, Vol.114, pp.27-38
摘要:Abstract(#br)Histamine has been reported to decrease the ultrafiltration coefficient, which inversely correlates with glomerular permselectivity, however the mechanism(s) underling this effect have never been investigated. This study aimed to assess whether histamine could e...
作者:Gianluca Miglio , Eleonora Veglia , Roberto Fantozzi
来源:[J].International Immunopharmacology(IF 2.417), 2015, Vol.28 (1), pp.215-219
摘要:Abstract(#br)Fumaric acid esters (FAEs) exert therapeutic effects in patients with psoriasis and multiple sclerosis, however their mode of action remains elusive. Pyroptosis is a caspase-1-dependent pro-inflammatory form of programmed cell death, mediated by the activation o...
作者:Eleonora Veglia , Maria Teresa Giraudo ...
来源:[J].BBA - Proteins and Proteomics(IF 3.733), 2016, Vol.1864 (2), pp.211-218
摘要:Abstract(#br)The adduction of fumaric acid to the sulfhydryl group of certain cysteine (Cys) residues in proteins via a Michael-like reaction leads to the formation of S -(2-succino)cysteine (2SC) sites. Although its role remains to be fully understood, this post-translational Cy...
作者:Eleonora Veglia , Cristina Grange ...
来源:[J].Inflammation Research(IF 1.964), 2015, Vol.64 (3-4), pp.261-270
摘要:Abstract(#br) Objective and design(#br)The aim of this study is to evaluate the expression of the histamine receptors, particularly focusing on the H4R in human renal tubules.(#br) Material(#br)The ex vivo evaluation was carried on specimens from human renal corte...
作者:Eleonora Veglia , Aldo Moggio
来源:[J].Inflammation Research(IF 1.964), 2015, Vol.64 (5), pp.271-273
摘要:Abstract(#br) Introduction(#br)To extend our previous observation of H4R upregulation in the kidney of diabetic rats, we evaluated in the same specimens the presence of the H3R.(#br) Materials and methods(#br)Kidney specimens from 24 8-week-old male Wistar r...
作者:Eleonora Veglia , Cristina Grange
来源:[B].Methods in Pharmacology and Toxicology2017
摘要:Abstract The best approach to study the complexity of renal pathophysiology is to use living organisms. However, to limit the number of animal experiments undertaken and obtain first in humans results, in vitro models can be extremely helpful options. Moreover, in vitro assays al...
作者:Alessandro Pini , Eleonora Veglia , Arianna Carolina Rosa
来源:[B].Methods in Pharmacology and Toxicology2017
摘要:Abstract Animal models have been, and for the foreseeable future, will remain pivotal to bridge the gap between the test tube and the human condition. In particular, the use of an animal model provides the unique chance to study the onset and the progression of renal disease, app...

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