全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Eleftherios P. Samartzis , Anne-Katrin Zimmermann ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:BRCA1/2-deficient ovarian carcinomas are recognized as target for Poly (ADP-ribose) polymerase (PARP) inhibitors. BRCA1 and BRCA2 proteins are involved in homologous recombination repair of double-strand DNA breaks. The relevance of other homologous recombination repair proteins,...
作者:Eleftherios P. Samartzis , Anna-Maria Schmidt ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:Endometrioid adenocarcinoma of the uterus and ovarian endometrioid carcinoma share many morphological and molecular features. Differentiation between simultaneous primary carcinomas and ovarian metastases of an endometrial cancer may be very challenging but is essential for progn...
作者:Eleftherios P. Samartzis , Konstantin J. Dedes ...
来源:[J].Fertility and Sterility(IF 4.174), 2013, Vol.100 (3), pp.770-776Elsevier
摘要:Objective(#br)To investigate whether histone deacetylase inhibitors reduce the expression of the G-protein-coupled estrogen receptor (GPER) and whether the functional inhibition of GPER by the antagonist G-15 decreases the proliferation of endometriotic cells.(#br)Design(#br...
作者:Eleftherios P. Samartzis , Anne-Katrin Zimmermann ...
来源:[J].2017, Vol.17 (1), pp.44BMC
摘要:BRCA1/2-deficient ovarian carcinomas are recognized as target for Poly (ADP-ribose) polymerase (PARP) inhibitors. BRCA1 and BRCA2 proteins are involved in homologous recombination repair of double-strand DNA breaks. The relevance of other homologous recombination repair prot...
作者:Eleftherios P. Samartzis , Anna-Maria Schmidt ...
来源:[J].2017, Vol.17 (1), pp.66BMC
摘要:Endometrioid adenocarcinoma of the uterus and ovarian endometrioid carcinoma share many morphological and molecular features. Differentiation between simultaneous primary carcinomas and ovarian metastases of an endometrial cancer may be very challenging but is essential for ...
作者:Eleftherios P. Samartzis , Patrick Imesch ...
来源:[J].Gynecological Endocrinology(IF 1.303), 2016, Vol.32 (7), pp.529-533Taylor & Francis
摘要:Abstract(#br)Endometriosis, a painful disorder associated with infertility, is estimated to occur in approximately 7–10% of reproductive age women. Although endometriosis is considered as an estrogen-dependent disease, the role of estrogen metabolites via receptor-independen...
作者:Eleftherios P. Samartzis , Michael Schneider ...
来源:[J].Fertility and Sterility(IF 4.174), 2010, Vol.95 (5), pp.1579-1583Elsevier
摘要:Objective(#br)To investigate whether the histone deacetylase (HDAC) inhibitor romidepsin down-regulates VEGF (vascular endothelial growth factor) gene expression and abrogates VEGF protein secretion in human epithelial endometriotic cells.(#br)Design(#br)In vitro study with ...
作者:Eleftherios P. Samartzis , Daniel Fink ...
来源:[J].2019, Vol.17 (1), pp.1BMC
摘要:Matrix metalloproteinases (MMPs), especially the gelatinases MMP-2 and MMP-9, play a crucial role in the pathogenesis of endometriosis by enabling invasion. Doxycycline is a well-tolerated antibiotic and a potent MMP-inhibitor in subantimicrobial doses. Gelatin zymography an...
作者:Eleftherios P. Samartzis , Aurelia Noske ...
来源:[J].PLOS ONE(IF 3.73), 2014, Vol.9 (1)PLOS
摘要:The G protein-coupled estrogen receptor (GPER) is a novel estrogen receptor that mediates proliferative effects induced by estrogen but also by tamoxifen. The aim of our study was to analyze the frequency of GPER in a large collective of primary invasive breast carcinomas, with s...

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