全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Eleftherios P. Samartzis , Anne-Katrin Zimmermann ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:BRCA1/2-deficient ovarian carcinomas are recognized as target for Poly (ADP-ribose) polymerase (PARP) inhibitors. BRCA1 and BRCA2 proteins are involved in homologous recombination repair of double-strand DNA breaks. The relevance of other homologous recombination repair proteins,...
作者:Eleftherios P. Samartzis , Anna-Maria Schmidt ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:Endometrioid adenocarcinoma of the uterus and ovarian endometrioid carcinoma share many morphological and molecular features. Differentiation between simultaneous primary carcinomas and ovarian metastases of an endometrial cancer may be very challenging but is essential for progn...
作者:Eleftherios P. Samartzis , Konstantin J. Dedes ...
来源:[J].Fertility and Sterility(IF 4.174), 2013, Vol.100 (3), pp.770-776Elsevier
摘要:Objective(#br)To investigate whether histone deacetylase inhibitors reduce the expression of the G-protein-coupled estrogen receptor (GPER) and whether the functional inhibition of GPER by the antagonist G-15 decreases the proliferation of endometriotic cells.(#br)Design(#br...
作者:Eleftherios P. Samartzis , Patrick Imesch ...
来源:[J].Gynecological Endocrinology(IF 1.303), 2016, Vol.32 (7), pp.529-533Taylor & Francis
摘要:Abstract(#br)Endometriosis, a painful disorder associated with infertility, is estimated to occur in approximately 7–10% of reproductive age women. Although endometriosis is considered as an estrogen-dependent disease, the role of estrogen metabolites via receptor-independen...
作者:Eleftherios P. Samartzis , Michael Schneider ...
来源:[J].Fertility and Sterility(IF 4.174), 2010, Vol.95 (5), pp.1579-1583Elsevier
摘要:Objective(#br)To investigate whether the histone deacetylase (HDAC) inhibitor romidepsin down-regulates VEGF (vascular endothelial growth factor) gene expression and abrogates VEGF protein secretion in human epithelial endometriotic cells.(#br)Design(#br)In vitro study with ...
作者:Eleftherios P. Samartzis , Aurelia Noske ...
来源:[J].PLOS ONE(IF 3.73), 2014, Vol.9 (1)PLOS
摘要:The G protein-coupled estrogen receptor (GPER) is a novel estrogen receptor that mediates proliferative effects induced by estrogen but also by tamoxifen. The aim of our study was to analyze the frequency of GPER in a large collective of primary invasive breast carcinomas, with s...
作者:Eleftherios P. Samartzis , Aurelia Noske ...
来源:[J].PLOS ONE(IF 3.73), 2014, Vol.9 (6)PLOS
摘要:To evaluate the frequency of MRE11/RAD50/NBS1 (MRN)-complex loss of protein expression in endometrial cancers (EC) and to determine whether loss of MRE11 renders the cancer cells sensitive to Poly(ADP-ribose) polymerase (PARP)-inhibitory treatment.;;MRN expression was examined in...
作者:Eleftherios P. Samartzis , Gabriele S. Merki-Feld ...
来源:[J].The European Journal of Contraception and Reproductive Health Care(IF 1.808), 2012, Vol.17 (3), pp.197-204Informa Healthcare
摘要:ABSTRACT Objectives Emergency contraception (EC) has been freely accessible in Swiss pharmacies since November 2002. Today some groups are still concerned that free access might result in less use of efficient contraceptive methods, overuse and more risky sexual behaviour. M...
作者:Eleftherios P. Samartzis , Aurelia Noske ...
来源:[J].Reproductive Sciences(IF 2.064), 2013, Vol.20 (12), pp.1416-1422SAGE
摘要:Class I histone deacetylases (HDACs-1-3) play an important role in steroid hormone–dependent gene expression and in modulatingcell survival and proliferation. We analyzed their expression in a tissue microarray including 74 endometriosis samples and30 normal endometrium cont...
作者:Eleftherios P. Samartzis , Aurelia Noske ...
来源:[J].Reproductive Sciences(IF 2.064), 2013, Vol.20 (12), pp.1416-1422SAGE
摘要:Class I histone deacetylases (HDACs-1-3) play an important role in steroid hormone–dependent gene expression and in modulatingcell survival and proliferation. We analyzed their expression in a tissue microarray including 74 endometriosis samples and30 normal endometrium cont...

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