全部文献期刊会议图书|学者科研项目
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作者:... Guido Sauter , Stefan Steurer , Eike Burandt
来源:[J].Gynecologic Oncology(IF 3.929), 2020, Vol.156 (3), pp.669-675
摘要:Abstract(#br)Objective(#br)Mismatch repair (MMR) deficiency and Bethesda panel microsatellite instability (MSI) are increasingly analyzed to identify tumors that might benefit from immune checkpoint inhibitors, but tumor heterogeneity is a potential obstacle for such analyses. In...
作者:Eike Burandt , Alexander Haese ...
来源:[J].Molecular Medicine(IF 4.469), 2020, Vol.26 (1), pp.1252-1259
摘要:Abstract(#br)Background(#br)TFAP2D is a transcription factor important for modulating gene expression in embryogenesis. Its expression and prognostic role in prostate cancer has not been evaluated. Methods(#br)Therefore, a tissue microarray containing 17,747 prostate cancer ...
作者:Eike Burandt , Thorsten Schlomm ...
来源:[J].Neoplasia, 2019, Vol.21 (9), pp.872-881
摘要:Abstract(#br)Dysregulation of S100A8 is described in many different human tumor types, but its role in prostate cancer is unknown. To evaluate the clinical relevance of S100A8 expression in prostate cancer, a tissue microarray containing 13,665 tumors was analyzed by immunohistoc...
作者:Eike Burandt , Till Sebastian Clauditz ...
来源:[J].Urologic Oncology: Seminars and Original Investigations(IF 3.647), 2019
摘要:Abstract(#br)Background(#br)Microsatellite instability (MSI), a hypermutator phenotype described in many cancers, has emerged as a predictive biomarker for immune checkpoint inhibitor therapy. Cancer heterogeneity represents a potential obstacle for the analysis of prediciti...
作者:Eike Burandt , Stefan Steurer ...
来源:[J].Disease Markers(IF 2.14), 2019, Vol.2019
摘要:Small-cell cancer of the urinary bladder is a rare but highly aggressive disease. It is currently unclear whether immune checkpoint therapies that have been approved for urothelial carcinomas will also be efficient in small-cell carcinomas. In this study, we analyzed potenti...
作者:Eike Burandt , Barbara Schmalfeldt ...
来源:[J].Gynecologic Oncology(IF 3.929), 2016, Vol.142 (3), pp.427-434
摘要:Abstract(#br)Objective(#br)Metastatic vulvar cancer is a rare disease. Information on metastatic patterns and corresponding prognosis or therapeutic approaches is scarce. We therefore analyzed pattern and course of metastatic disease in a large single center cohort.(#br)Meth...
作者:Eike Burandt , Patrick Lebok ...
来源:[J].Acta Oncologica(IF 2.867), 2020, Vol.59 (3), pp.268-273
摘要:Abstract(#br)Background:(#br) Remodelling and spacing factor 1 (RSF1) is involved in the regulation of chromatin remodelling and represents a potential therapeutic target. High RSF1 expression has been linked to adverse tumour features in many cancer types, but its role in p...
作者:Eike Burandt , Martin Grünert ...
来源:[J].Breast Cancer(IF 1.33), 2016, Vol.23 (1), pp.111-119
摘要:Abstract(#br) Background(#br)Cyclin D1 (CCND1) gene amplification is a molecular key alteration in breast cancer and was suggested to predict resistance to antihormonal therapy. As tissue heterogeneity may affect diagnostic accuracy of predictive biomarkers, CCND1 genetic he...
作者:Eike Burandt , Phillip Stahl ...
来源:[J].Urologic Oncology: Seminars and Original Investigations(IF 3.647), 2014, Vol.32 (8), pp.1225-1233
摘要:Abstract(#br)Objective(#br)Although most patients with urinary bladder cancer present with noninvasive and low-malignant stages of the disease, about 20% eventually develop life-threatening metastatic tumors. This study was designed to evaluate the potential of matrix-assisted la...

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