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作者:M. Escher , E.F. Stange , K.R. Herrlinger
来源:[J].Journal of Crohn's and Colitis(IF 3.385), 2010, Vol.4 (5), pp.606-609
摘要:Abstract(#br)Here we report 2 cases of fatal Pneumocystis jirovecii pneumonia in patients with severe ulcerative colitis receiving combination immunosuppression including tacrolimus. We discuss the necessity of a P. jirovecii prophylaxis especially in elderly patients according t...
作者:... B. Dietrich , B. Hentsch , E.F. Stange
来源:[J].Journal of Crohn's and Colitis(IF 3.385), 2013, Vol.7 (8), pp.636-643
摘要:Abstract(#br)Background(#br)Vidofludimus (SC12267) is a novel oral immunomodulator inhibiting dihydroorotate dehydrogenase (DHODH) and the expression of proinflammatory cytokines including interleukin-17 (IL17A and IL17F) and interferon-gamma. The objective of the study was to ex...

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